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Bharatendu Swain

Abstract Background Scar visibility is a major deterrent to patients seeking reconstructive surgery. Endoscopic surgery can address a wide range of problems, from minimizing or concealing scars to improving access and outcomes in certain situations. This case series includes a wide range of reconstructive surgery problems addressed by subcutaneous endoscopic surgery. Having one or more trained assistants is a major deterrent to the performance of endoscopic surgery by the lone practitioner. The single (or two-port technique for muscle harvest) used in most cases simplifies subcutaneous endoscopic surgery. Methods A single-port endoscopy technique, with a 4-mm, 30-degree side viewing telescope and sheath, optical camera and cold light source, was used. Case records were reviewed for access incisions, procedure abandonment, postoperative pain, complications, and patient satisfaction. Results A total of 53 endoscopic surgical episodes between 2003 and 2013 were reviewed. Using a single port, most cases were done successfully. The access site was changed peroperatively in one case. Complications included transient nerve palsy in one case, which recovered completely. There was minimal intraoperative bleeding. Postoperative pain was low except in one case and managed with minimal analgesia. Patient satisfaction was high in all cases. Conclusions Subsurface endoscopy done on a wide range of reconstructive surgery procedures and resulted in minimal scars and high patient satisfaction.

2021 ◽  
Simon Thomas van Baal ◽  
Antonio Verdejo-García ◽  
Jakob Hohwy

Background During the COVID-19 pandemic, public health departments have issued guidelines to limit viral transmission. In this environment, people will feel urges to engage in activities that violate these guidelines, but research on guideline adherence has been reliant on surveys asking people to self-report their typical behaviour, which may fail to capture these urges as they unfold. Guideline adherence could be improved through behaviour change interventions, but considering the wide range of behaviours that COVID-19 guidelines prescribe, few methods allow observing changes of aggregate guideline adherence in the wild. Methods To administer interventions and to obtain contemporaneous data on a wide range of behaviours, we use ecological momentary assessment. In this preregistered parallel randomised trial, 95 participants aged 18-65 from the UK were assigned to three conditions using blinded block randomisation, and engage in episodic future thinking (n = 33), compassion exercises (n = 31), or a sham procedure (n = 31) and report regularly on the intensity of their occurrent urges (min. 1, max. 10) and their ability to control them. We investigate whether state impulsivity and vaccine attitudes predict guideline adherence while assessing through which mechanism these predictors affect behaviour. Results We found that episodic future thinking (b = -1.60) and compassion exercises (b = -1.40) reduce the intensity of urges. State impulsivity is associated with stronger urges, but we found no evidence that vaccine hesitancy predicts lesser self-control. Conclusions We conclude that episodic future thinking exercises and compassion training may be used to stimulate compliance of individuals who are a risk for the community, such as those in voluntary self-isolation.

Shengchao Yu ◽  
Mingkun Yang ◽  
Jie Xiong ◽  
Qi Zhang ◽  
Xinxin Gao ◽  

Cyanobacteria are a large group of prokaryotes capable of oxygenic photosynthesis and play a vital role in nitrogen and carbon cycles on Earth. Nostoc 7120 is a commonly used model cyanobacterium for studying cell differentiation and nitrogen metabolism. In this study, we presented the first comprehensive draft map of the Nostoc 7120 proteome and a wide range of posttranslational modifications.

2021 ◽  
Vol 75 (9) ◽  
pp. 766-771
Theo Ralla ◽  
Roland Schex ◽  
Fabiola Porta ◽  
Christian Schäfer

The formulation of active ingredients into emulsion- and suspension-based delivery systems offers a wide range of opportunities to produce stable and highly bioavailable product forms for their later application in human and animal nutrition. Recent trends in product form development have focused on using renewable and naturally-derived raw materials to meet the increasing consumer demand on sustainable value chains and nutritional products with 'clean labelling'. Therefore, we reviewed chemical fundamentals and application examples of plant-derived protective hydrocolloids with highly potent emulsifying capacity, in particular, modified starches, pectin, and lignosulfonates, for the formulation of vitamins, carotenoids, and other active ingredients.

2021 ◽  
Daryl S. Sequeira ◽  
Okechukwu M. Egbukole ◽  
Ahmed M. Sahl

Abstract High quality composition and PVT data can directly improve a wide range of upstream and downstreamengineering calculations. The quality of PVT Black oil experiments depends on awide variety of factors that includes type of PVT system, pressure-temperature conditions, stability and composition. The objective of this study is to emphasize the need to use material balance calculations obtainedfrom separator test data to back-calculate the reservoir composition andvalidate it against the original reservoir fluid composition. The methodologies employed in this study involve the following steps;

Catalysts ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 1107
Zhuoying Jiang ◽  
Jiajie Hu ◽  
Matthew Tong ◽  
Anna C. Samia ◽  
Huichun (Judy) Zhang ◽  

This paper describes an innovative machine learning (ML) model to predict the performance of different metal oxide photocatalysts on a wide range of contaminants. The molecular structures of metal oxide photocatalysts are encoded with a crystal graph convolution neural network (CGCNN). The structure of organic compounds is encoded via digital molecular fingerprints (MF). The encoded features of the photocatalysts and contaminants are input to an artificial neural network (ANN), named as CGCNN-MF-ANN model. The CGCNN-MF-ANN model has achieved a very good prediction of the photocatalytic degradation rate constants by different photocatalysts over a wide range of organic contaminants. The effects of the data training strategy on the ML model performance are compared. The effects of different factors on photocatalytic degradation performance are further evaluated by feature importance analyses. Examples are illustrated on the use of this novel ML model for optimal photocatalyst selection and for assessing other types of photocatalysts for different environmental applications.

Drones ◽  
2021 ◽  
Vol 5 (3) ◽  
pp. 98
Jian Zhang ◽  
Hailong Huang

Unmanned Aerial Vehicles (UAVs) have become necessary tools for a wide range of activities including but not limited to real-time monitoring, surveillance, reconnaissance, border patrol, search and rescue, civilian, scientific and military missions, etc. Their advantage is unprecedented and irreplaceable, especially in environments dangerous to humans, for example, in radiation or pollution-exposed areas. Two path-planning algorithms for reconnaissance and surveillance are proposed in this paper, which ensures every point on the target ground area can be seen at least once in a complete surveillance circle. Moreover, the geometrically complex environments with occlusions are considered in our research. Compared with many existing methods, we decompose this problem into a waypoint-determination problem and an instance of the traveling-salesman problem.

2021 ◽  
Csilla Ariese ◽  
Magdalena Wróblewska

The cry for decolonization has echoed throughout the museum world. Although perhaps most audibly heard in the case of ethnographic museums, many different types of museums have felt the need to engage in decolonial practices. Amidst those who have argued that an institution as deeply colonial as the museum cannot truly be decolonized, museum staff and museologists have been approaching the issue from different angles to practice decoloniality in any way they can. This book collects a wide range of practices from museums whose audiences, often highly diverse, come together in sometimes contentious conversations about pasts and futures. Although there are no easy or uniform answers as to how best to deal with colonial pasts, this collection of practices functions as an accessible toolkit from which museum staff can choose in order to experiment with and implement methods according to their own needs and situations. The practices are divided thematically and include, among others, methods for decentering, improving transparency, and increasing inclusivity.

2021 ◽  

The history of childhood and welfare in Britain through the eyes of children. 'Children’s Experiences of Welfare in Modern Britain' brings together the latest research as provided by the state, charities and families from 1830 to 1980. Demonstrating how the young were integral to the making, interpretation, delivery and impact of welfare services, the chapters consider a wide range of investments in young people’s lives, including residential institutions, emigration schemes, hospitals and clinics, schools, social housing and familial care. Drawing upon thousands of personal testimonies, including a wealth of writing by children themselves, the book shows that we can only understand the history and impact of welfare if we listen to children’s experiences.

2021 ◽  
Vol 14 ◽  
Shan Xu ◽  
Wei Li ◽  
Jing Wu ◽  
Yuru Lu ◽  
Ming Xie ◽  

: MiRNA-129-5p belongs to the microRNA-129 (miRNA-129) family. MiRNA-129-5p is expressed in many tissues and organs of the human body, and it regulates a wide range of biological functions. The abnormal expression of miRNA-129-5p is related to the occurrence and development of a variety of malignant tumors. MiRNA-129-5p plays an important role in the tumorigenesis process and functions by promoting or inhibiting tumors. However, the role of miRNA-129-5p in cancer remains controversial. This article reviews the different biological functions of miRNA-129-5p in cancer and provides ideas for research in this field to guide the development of targeted therapies and drugs for malignant tumors.

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