Nasal pleomorphic adenoma with skeletal muscle differentiation: Potential misdiagnosis as rhabdomyosarcoma

1997 ◽  
Vol 28 (11) ◽  
pp. 1299-1302 ◽  
Author(s):  
Polly W.Y Lam ◽  
John K.C Chan ◽  
Vat-Chong Sin
Keyword(s):  
Skeletal Muscle ◽  
Pleomorphic Adenoma ◽  
Muscle Differentiation ◽  
Skeletal Muscle Differentiation ◽  
Differentiation Potential

scholarly journals The requirement of Mettl3-promoted MyoD mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation

Open Biology ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. 170119 ◽  
Author(s):  
Kensuke Kudou ◽  
Tetsuro Komatsu ◽  
Jumpei Nogami ◽  
Kazumitsu Maehara ◽  
Akihito Harada ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Untranslated Region ◽  
Mrna Level ◽  
Muscle Differentiation ◽  
Skeletal Muscle Differentiation ◽  
Differentiation Potential ◽  
Cycle Arrest ◽  
Rna Knockdown ◽  
Myod Expression ◽  
Myogenic Progenitor

Myogenic progenitor/stem cells retain their skeletal muscle differentiation potential by maintaining myogenic transcription factors such as MyoD. However, the mechanism of how MyoD expression is maintained in proliferative progenitor cells has not been elucidated. Here, we found that MyoD expression was reduced at the mRNA level by cell cycle arrest in S and G2 phases, which in turn led to the absence of skeletal muscle differentiation. The reduction of MyoD mRNA was correlated with the reduced expression of factors regulating RNA metabolism, including methyltransferase like 3 (Mettl3), which induces N 6 -methyladenosine (m 6 A) modifications of RNA. Knockdown of Mettl3 revealed that MyoD RNA was specifically downregulated and that this was caused by a decrease in processed, but not unprocessed, mRNA. Potential m 6 A modification sites were profiled by m 6 A sequencing and identified within the 5′ untranslated region (UTR) of MyoD mRNA. Deletion of the 5′ UTR revealed that it has a role in MyoD mRNA processing. These data showed that Mettl3 is required for MyoD mRNA expression in proliferative myoblasts.

Skeletal muscle differentiation potential of human adult bone marrow cells

2004 ◽  
Vol 295 (1) ◽  
pp. 66-78 ◽  
Author(s):  
Patrizia Bossolasco ◽  
Stefania Corti ◽  
Sandra Strazzer ◽  
Chiara Borsotti ◽  
Roberto Del Bo ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Muscle Differentiation ◽  
Skeletal Muscle Differentiation ◽  
Differentiation Potential ◽  
Adult Bone Marrow ◽  
Human Adult ◽  
Adult Bone ◽  
Marrow Cells

scholarly journals The expression of nestin delineates skeletal muscle differentiation in the developing rat esophagus

2011 ◽  
Vol 218 (3) ◽  
pp. 311-323 ◽  
Author(s):  
Peng-Han Su ◽  
Tung-Cheng Wang ◽  
Zong-Ruei Wong ◽  
Bu-Miin Huang ◽  
Hsi-Yuan Yang
Keyword(s):  
Skeletal Muscle ◽  
Muscle Differentiation ◽  
Skeletal Muscle Differentiation ◽  
Developing Rat

scholarly journals Post-transcriptional modulation of interleukin 8 by CNOT6L regulates skeletal muscle differentiation

2016 ◽  
Vol 1863 (2) ◽  
pp. 263-270 ◽  
Author(s):  
Anna Polesskaya ◽  
Guillaume Pinna ◽  
Yassine Sassi ◽  
Marie Vandamme ◽  
Anne Bigot ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Differentiation ◽  
Interleukin 8 ◽  
Skeletal Muscle Differentiation ◽  
Transcriptional Modulation
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