Baseline Topographic Optic Disc Measurements Are Associated With the Development of Primary Open-Angle Glaucoma: The Confocal Scanning Laser Ophthalmoscopy Ancillary Study to the Ocular Hypertension Treatment Study

2006 ◽  
Vol 2006 ◽  
pp. 57-58
Author(s):  
J.S. Myers
Keyword(s):  
Ocular Hypertension ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Scanning Laser Ophthalmoscopy ◽  
Hypertension Treatment ◽  
Open Angle ◽  
Ancillary Study ◽  
Confocal Scanning Laser Ophthalmoscopy ◽  
Confocal Scanning ◽  
Confocal Scanning Laser

scholarly journals The role of confocal scanning laser ophthalmoscopy in stereometric differentiation of eye papilla in ocular hypertension, normal tension glaucoma and primary open-angle glaucoma

2013 ◽  
Vol 70 (3) ◽  
pp. 304-308
Author(s):  
Ranko Gvozdenovic ◽  
Dusica Risovic ◽  
Ivan Marjanovic ◽  
Miroslav Stamenkovic ◽  
Zorica Jokovic ◽  
...  
Keyword(s):  
Ocular Hypertension ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Normal Tension Glaucoma ◽  
Scanning Laser Ophthalmoscopy ◽  
Open Angle ◽  
Neuroretinal Rim ◽  
Confocal Scanning Laser Ophthalmoscopy ◽  
Confocal Scanning ◽  
Confocal Scanning Laser

Background/Aim. Primary open angle glaucoma (POAG) and normal tension glaucoma (NTG) demonstrate the same structural changes in the optic disc along with visual field defects but only POAG includes an abnormal elevation of intraocular pressure. Heidelberg retina tomograph based on confocal scanning laser ophthalmoscopy (HRT) and Moorfields regression analysis (MRA) have been employed to quantitatively assess the topography of eye papilla. We measured stereographic parameters of eye papilla in patients with POAG, NTG, and ocular hypertension (OH) using an HRT in order to determine whether HRT topographic parameters can be used to differentiate those conditions. Methods. The results of 145 eyes of 145 patients with OH, NTG and POAG were analyzed by age, refractive error, quality of HRT images, stereometric and MRA parameters. Results. Significant differences were found between NTG and other two groups for a majority of the HRT parameters, and also no differences between OH and POAG patients for a majority of the investigated parameters, except thickness of retinal nerve fiber layer. By reading the MRA no differences were found in the distribution of mostly damaged and mostly preserved neuroretinal rim sectors between NTG and POAG patients, and also all sectors of the neuroretinal rim in OH patients were preserved. Conclusion. HRT stereometric parameters are useful to differentiate patients with OH and NTG, and also for differentiation between NTG and POAG patients, but most of parameters showed no difference between OH and POAG patients. MRA may serve to confirm the diagnosis of OH, but not for precise distinction between NTG and POAG.

Topical Ocular Hypotensive Medication to Delay or Prevent the Onset of Primary Open-Angle Glaucoma

2020 ◽  
pp. 85-90
Author(s):  
Alan D. Penman ◽  
Kimberly W. Crowder ◽  
William M. Watkins
Keyword(s):  
Ocular Hypertension ◽  
Central Corneal Thickness ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Corneal Thickness ◽  
Field Pattern ◽  
Controlled Clinical Trial ◽  
Glaucomatous Optic Neuropathy ◽  
Hypertension Treatment ◽  
Open Angle

The Ocular Hypertension Treatment Study (OHTS) was a randomized, open, placebo-controlled, clinical trial to determine whether reducing intraocular pressure (IOP) in eyes with ocular hypertension (OHTN) reduced the risk of developing primary open-angle glaucoma (POAG). The study found that topical ocular hypotensive medication was effective in delaying or preventing the development of glaucomatous optic neuropathy in eyes with OHTN. However, the authors recommended stratifying risk in patients with OHTN using variables such as baseline age, vertical and horizontal cup-to-disc ratio, visual field pattern standard deviation, IOP, and, especially, central corneal thickness.

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