Bioequivalence of two formulations of ketotifen fumarate ophthalmic solution: A single-center, randomized, double-masked conjunctival allergen challenge investigation in allergic conjunctivitis

Clinical Therapeutics ◽

10.1016/s0149-2918(08)80051-3 ◽

2008 ◽

Vol 30 (7) ◽

pp. 1272-1282 ◽

Author(s):

Gail L. Torkildsen ◽

Mark B. Abelson ◽

Paul J. Gomes

Keyword(s):

Allergic Conjunctivitis ◽

Allergen Challenge ◽

Ophthalmic Solution ◽

Single Center ◽

Ketotifen Fumarate ◽

Conjunctival Allergen Challenge

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Efficacy of Ketotifen Fumarate 0.025% Ophthalmic Solution Compared With Placebo in the Conjunctival Allergen Challenge Model

Archives of Ophthalmology ◽

10.1001/archopht.121.5.626 ◽

2003 ◽

Vol 121 (5) ◽

pp. 626 ◽

Author(s):

Mark B. Abelson

Keyword(s):

Allergen Challenge ◽

Ophthalmic Solution ◽

Ketotifen Fumarate ◽

Conjunctival Allergen Challenge

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Emedastine ophthalmic solution 0.05% versus levocabastine ophthalmic suspension 0.05% in the treatment of allergic conjunctivitis using the conjunctival allergen challenge model

American Journal of Ophthalmology ◽

10.1016/s0002-9394(00)00689-9 ◽

2000 ◽

Vol 130 (6) ◽

pp. 717-723 ◽

Author(s):

Peter A Netland ◽

Charles Leahy ◽

Kathleen L Krenzer

Keyword(s):

Allergic Conjunctivitis ◽

Allergen Challenge ◽

Ophthalmic Solution ◽

Conjunctival Allergen Challenge ◽

Ophthalmic Suspension

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Comparison of ketotifen fumarate ophthalmic solution alone, desloratadine alone, and their combination for inhibition of the signs and symptoms of seasonal allergic rhinoconjunctivitis in the conjunctival allergen challenge model: a double-masked, placebo- and active-controlled trial

Clinical Therapeutics ◽

10.1016/s0149-2918(03)80199-6 ◽

2003 ◽

Vol 25 (7) ◽

pp. 1975-1987 ◽

Author(s):

H.Jerome Crampton

Keyword(s):

Controlled Trial ◽

Allergen Challenge ◽

Ophthalmic Solution ◽

Signs And Symptoms ◽

Allergic Rhinoconjunctivitis ◽

Ketotifen Fumarate ◽

Conjunctival Allergen Challenge

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Phase III trials examining the efficacy of cetirizine ophthalmic solution 0.24% compared to vehicle for the treatment of allergic conjunctivitis in the conjunctival allergen challenge model

Clinical Ophthalmology ◽

10.2147/opth.s185835 ◽

2018 ◽

Vol Volume 12 ◽

pp. 2617-2628 ◽

Author(s):

Edward Meier ◽

Gail Torkildsen ◽

Paul Gomes ◽

Mark C. Jasek

Keyword(s):

Allergic Conjunctivitis ◽

Allergen Challenge ◽

Ophthalmic Solution ◽

Phase Iii ◽

Phase Iii Trials ◽

Conjunctival Allergen Challenge

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A comparison of the relative clinical efficacy of a single dose of ketotifen fumarate 0.025% ophthalmic solution versus placebo in inhibiting the signs and symptoms of allergic rhinoconjunctivitis as induced by the conjunctival allergen challenge model

Clinical Therapeutics ◽

10.1016/s0149-2918(02)80080-7 ◽

2002 ◽

Vol 24 (11) ◽

pp. 1800-1808 ◽

Author(s):

H. Jerome Cramptom

Keyword(s):

Single Dose ◽

Clinical Efficacy ◽

Allergen Challenge ◽

Ophthalmic Solution ◽

Signs And Symptoms ◽

Allergic Rhinoconjunctivitis ◽

Solution Versus ◽

Ketotifen Fumarate ◽

Conjunctival Allergen Challenge

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A Single-Center, Double Masked, Randomized, Placebo Controlled Study to Evaluate the Efficacy of Multiple Doses of 10 mg Montelukast Sodium (Singulair®) on the Signs and Symptoms of Allergic Conjunctivitis Using the Conjunctival Allergen Challenge (CAC) Model

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2006.11.258 ◽

2007 ◽

Vol 119 (1) ◽

pp. S60 ◽

Author(s):

P.J. Gomes ◽

M.B. Abelson

Keyword(s):

Allergic Conjunctivitis ◽

Allergen Challenge ◽

Signs And Symptoms ◽

Controlled Study ◽

Single Center ◽

Montelukast Sodium ◽

Multiple Doses ◽

Conjunctival Allergen Challenge

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Evaluation of Comfort Using Olopatadine Hydrochloride 0.1% Ophthalmic Solution in the Treatment of Allergic Conjunctivitis in Contact Lens Wearers Compared to Placebo Using the Conjunctival Allergen-Challenge Model

Eye & Contact Lens Science & Clinical Practice ◽

10.1097/01.icl.0000063576.32087.f7 ◽

2003 ◽

Vol 29 (2) ◽

pp. 113-116 ◽

Author(s):

Miguel Brodsky ◽

William E. Berger ◽

Salim Butrus ◽

Arthur B. Epstein ◽

Murat Irkec

Keyword(s):

Contact Lens ◽

Allergic Conjunctivitis ◽

Allergen Challenge ◽

Ophthalmic Solution ◽

Conjunctival Allergen Challenge ◽

Olopatadine Hydrochloride

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Randomized, double-masked, placebo-controlled comparison of the efficacy of emedastine difumarate 0.05% ophthalmic solution and ketotifen fumarate 0.025% ophthalmic solution in the human conjunctival allergen challenge model

Clinical Therapeutics ◽

10.1016/s0149-2918(02)85042-1 ◽

2002 ◽

Vol 24 (3) ◽

pp. 409-416 ◽

Author(s):

Peter A. D'Arienzo ◽

Andrea Leonardi ◽

George Bensch

Keyword(s):

Allergen Challenge ◽

Ophthalmic Solution ◽

Ketotifen Fumarate ◽

Conjunctival Allergen Challenge

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Phase 3 Randomized Double-Masked Study of Efficacy and Safety of Once-Daily 0.77% Olopatadine Hydrochloride Ophthalmic Solution in Subjects With Allergic Conjunctivitis Using the Conjunctival Allergen Challenge Model

Cornea ◽

10.1097/ico.0000000000000562 ◽

2015 ◽

Vol 34 (10) ◽

pp. 1245-1251 ◽

Author(s):

Eugene McLaurin ◽

Abhijit Narvekar ◽

Paul Gomes ◽

Adeniyi Adewale ◽

Gail Torkildsen

Keyword(s):

Allergic Conjunctivitis ◽

Allergen Challenge ◽

Ophthalmic Solution ◽

Efficacy And Safety ◽

Phase 3 ◽

Conjunctival Allergen Challenge ◽

Olopatadine Hydrochloride

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Bepotastine Besilate Ophthalmic Solution 1.5% Produces Strong Clinical Benefit for Ocular Itching Immediately Following Dosing in the Conjunctival Allergen Challenge (CAC) Model of Allergic Conjunctivitis

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2010.12.1021 ◽

2011 ◽

Vol 127 (2) ◽

pp. AB256-AB256

Author(s):

J.C. Clark ◽

J.I. Williams ◽

P.J. Gomes ◽

M.B. Abelson ◽

J.A. Gow ◽

...

Keyword(s):

Clinical Benefit ◽

Allergic Conjunctivitis ◽

Allergen Challenge ◽

Ophthalmic Solution ◽

Ocular Itching ◽

Conjunctival Allergen Challenge

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