HBY 097 - a second-generation nonnucleoside inhibitor of the HIV-1 reverse transcriptase

Pharmacochemistry Library - Trends in Drug Research II, Proceedings of the 11th Noordwijkerhout-Camerino Symposium ◽

10.1016/s0165-7208(98)80050-0 ◽

1998 ◽

pp. 117-119

Author(s):

Jörg-Peter Kleim

Keyword(s):

Reverse Transcriptase ◽

Second Generation ◽

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ChemInform Abstract: The Design and Synthesis of Diaryl Ether Second Generation HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs) with Enhanced Potency versus Key Clinical Mutations.

10.1002/chin.200837210 ◽

2008 ◽

Vol 39 (37) ◽

Author(s):

Thomas J. Tucker ◽

et al. et al.

Keyword(s):

Reverse Transcriptase ◽

Second Generation ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design And Synthesis ◽

Diaryl Ether ◽

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SENSE makes us rethink the second-generation nonnucleoside reverse transcriptase inhibitor etravirineʼs place in HIV-1 treatment

AIDS ◽

10.1097/qad.0b013e328342fc22 ◽

2011 ◽

Vol 25 (3) ◽

pp. 383-384

Author(s):

Jade Ghosn

Keyword(s):

Reverse Transcriptase ◽

Second Generation ◽

Transcriptase Inhibitor ◽

Nonnucleoside Reverse Transcriptase Inhibitor ◽

Reverse Transcriptase Inhibitor ◽

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The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2008.03.064 ◽

2008 ◽

Vol 18 (9) ◽

pp. 2959-2966 ◽

Author(s):

Thomas J. Tucker ◽

Sandeep Saggar ◽

John T. Sisko ◽

Robert M. Tynebor ◽

Theresa M. Williams ◽

...

Keyword(s):

Reverse Transcriptase ◽

Second Generation ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design And Synthesis ◽

Diaryl Ether ◽

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Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors 1 1Edited by J. Karn

Journal of Molecular Biology ◽

10.1006/jmbi.2001.4988 ◽

2001 ◽

Vol 312 (4) ◽

pp. 795-805 ◽

Author(s):

J Ren ◽

C Nichols ◽

L Bird ◽

P Chamberlain ◽

K Weaver ◽

...

Keyword(s):

Drug Resistance ◽

Reverse Transcriptase ◽

Second Generation ◽

Structural Mechanisms ◽

Nucleoside Inhibitors ◽

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Binding of the Second Generation Non-nucleoside Inhibitor S-1153 to HIV-1 Reverse Transcriptase Involves Extensive Main Chain Hydrogen Bonding

Journal of Biological Chemistry ◽

10.1074/jbc.275.19.14316 ◽

2000 ◽

Vol 275 (19) ◽

pp. 14316-14320 ◽

Author(s):

Jingshan Ren ◽

Charles Nichols ◽

Louise E. Bird ◽

Tamio Fujiwara ◽

Hirohiko Sugimoto ◽

...

Keyword(s):

Hydrogen Bonding ◽

Reverse Transcriptase ◽

Second Generation ◽

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Second-generation non-nucleosidic reverse transcriptase inhibitor HBY097 and HIV-1 viral load

10.1016/s0140-6736(97)24021-3 ◽

1997 ◽

Vol 349 (9064) ◽

pp. 1517 ◽

Author(s):

Helga Rübsamen-Waigmann ◽

Edward Huguenel ◽

Arno Paessens ◽

Jörg-Peter Kleim ◽

Mark A Wainberg ◽

...

Keyword(s):

Reverse Transcriptase ◽

Second Generation ◽

Transcriptase Inhibitor ◽

Reverse Transcriptase Inhibitor ◽

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3 Discovery of Second Generation Quinazolinone Non-Nucleoside Reverse Transcriptase Inhibitors of Hiv-1

Progress in Medicinal Chemistry ◽

10.1016/s0079-6468(08)70082-1 ◽

2002 ◽

pp. 63-105 ◽

Author(s):

Jeffrey W. Corbett ◽

James D. Rodgers

Keyword(s):

Reverse Transcriptase ◽

Second Generation ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

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Minority Variants Associated with Transmitted and Acquired HIV-1 Nonnucleoside Reverse Transcriptase Inhibitor Resistance: Implications for the Use of Second-Generation Nonnucleoside Reverse Transcriptase Inhibitors

JAIDS Journal of Acquired Immune Deficiency Syndromes ◽

10.1097/qai.0b013e3181bca669 ◽

2009 ◽

Vol 52 (3) ◽

pp. 309-315 ◽

Author(s):

Vici Varghese ◽

Rajin Shahriar ◽

Soo-Yon Rhee ◽

Tommy Liu ◽

Birgitte B Simen ◽

...

Keyword(s):

Reverse Transcriptase ◽

Second Generation ◽

Transcriptase Inhibitor ◽

Reverse Transcriptase Inhibitors ◽

Nonnucleoside Reverse Transcriptase Inhibitors ◽

Nonnucleoside Reverse Transcriptase Inhibitor ◽

Minority Variants ◽

Inhibitor Resistance ◽

Reverse Transcriptase Inhibitor ◽

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Characterization of HIV-1 reverse transcriptase drug resistance connection subdomain mutation N348I

10.32469/10355/14917 ◽

2011 ◽

Author(s):

Matthew M. Schuckmann

Keyword(s):

Drug Resistance ◽

Reverse Transcriptase ◽

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QSAR study by the RASMS method of DABO derivatives as HIV-1 reverse transcriptase non-nucleoside inhibitors

Журнал структурной химии ◽

10.26902/jsc20170720 ◽

2017 ◽

Vol 58 (7) ◽

pp. 1457-1465

Author(s):

J.-B. Tong ◽

◽

M. Bai ◽

X. Zhao ◽

◽

...

Keyword(s):

Reverse Transcriptase ◽

Nucleoside Inhibitors ◽

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