Significance of QTc prolongation on ventricular arrhythmias in patients with left ventricular hypertrophy secondary to essential hypertension

1998 ◽  
Vol 64 (2) ◽  
pp. 179-184 ◽  
Author(s):  
Kaan Kulan ◽  
Dilek Ural ◽  
Baki Komsuoğlu ◽  
Ayşen Ağaçdiken ◽  
Özhan Göldeli ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Arrhythmias ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Qtc Prolongation

scholarly journals Is hypertensive left ventricular hypertrophy a cause of sustained ventricular arrhythmias in humans?

2021 ◽  
Author(s):  
R. Nadarajah ◽  
P. A. Patel ◽  
M. H. Tayebjee
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Ventricular Arrhythmias ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Systemic Hypertension ◽  
Electrolyte Disturbance ◽  
Electrocardiographic Monitoring ◽  
Homogenous Distribution ◽  
Artery Disease ◽  
Asymptomatic Coronary Artery Disease

AbstractSudden cardiac death (SCD) is most commonly secondary to sustained ventricular arrhythmias (VAs). This review aimed to evaluate if left ventricular hypertrophy (LVH) secondary to systemic hypertension in humans is an isolated risk factor for ventricular arrhythmogenesis. Animal models of hypertensive LVH have shown changes in ion channel function and distribution, gap junction re-distribution and fibrotic deposition. Clinical data has consistently exhibited an increase in prevalence and complexity of non-sustained VAs on electrocardiographic monitoring. However, there is a dearth of trials suggesting progression to sustained VAs and SCD, with extrapolations being confounded by presence of co-existent asymptomatic coronary artery disease (CAD). Putatively, this lack of data may be due to the presence of more homogenous distribution of pathophysiological changes seen in those with hypertensive LVH versus known pro-arrhythmic conditions such as HCM and myocardial infarction. The overall impression is that sustained VAs in the context of hypertensive LVH are most likely to be precipitated by other causes such as CAD or electrolyte disturbance.

scholarly journals Cardiac Arrhythmias and Left Ventricular Hypertrophy in Dipper and Nondipper Patients With Essential Hypertension

2000 ◽  
Vol 64 (7) ◽  
pp. 499-504 ◽  
Author(s):  
Hiroshi Ijiri ◽  
Isao Kohno ◽  
DongFeng Yin ◽  
Hiroshi Iwasaki ◽  
Masahiro Takusagawa ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Left Ventricular Hypertrophy ◽  
Cardiac Arrhythmias ◽  
Ventricular Hypertrophy ◽  
Left Ventricular

Risk of ventricular arrhythmias in left ventricular hypertrophy: The Framingham Heart Study

1987 ◽  
Vol 60 (7) ◽  
pp. 560-565 ◽  
Author(s):  
Daniel Levy ◽  
Keaven M. Anderson ◽  
Daniel D. Savage ◽  
Susan A. Balkus ◽  
William B. Kannel ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Framingham Heart Study ◽  
Ventricular Arrhythmias ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Heart Study
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