P1107 : Unconsidered misuse of acetaminophen is one of the causal cofactors of acute liver failure in adults with severe dengue fever

2015 ◽  
Vol 62 ◽  
pp. S765
Author(s):  
M. Gelu-Simeon ◽  
C. Francoz ◽  
P. Ichai ◽  
A. Cabie ◽  
E. Saillard ◽  
...  
2020 ◽  
Vol 8 ◽  
pp. 2050313X2091342 ◽  
Author(s):  
Navaneethakrishnan Suganthan ◽  
Gajawathana Sakthilingham ◽  
Thirunavukarasu Kumanan

Dengue is the most common arboviral disease, the presentation of which ranges from asymptomatic illness to dengue shock syndrome. Liver is the most common organ affected in dengue, and liver involvement is asymptomatic in majority. Dengue fever is a rare, but a leading cause for acute liver failure in endemic regions. Here, we report a case of a 34-year-old male ethanol user (16 units per week), presented with typical features of dengue infection, which was confirmed serologically, complicated with acute liver failure without clinical, radiological or laboratory evidence of plasma leakage. He was managed with intravenous fresh frozen plasma and N-acetyl cysteine along with other recommended supportive therapies for acute hepatic failure. He made an uneventful recovery.


2016 ◽  
Vol 62 (3) ◽  
pp. 200-205 ◽  
Author(s):  
Kamolwish Laoprasopwattana ◽  
Puthachat Jundee ◽  
Pornpimol Pruekprasert ◽  
Alan Geater

Hepatology ◽  
2019 ◽  
Vol 70 (5) ◽  
pp. 1863-1865 ◽  
Author(s):  
Antonio Galante ◽  
Oyedele Adeyi ◽  
Lawrence Lau ◽  
Atul Humar ◽  
Zita Galvin ◽  
...  

2011 ◽  
Vol 4 (4) ◽  
pp. 323-324 ◽  
Author(s):  
Rajat Jhamb ◽  
Bineeta Kashyap ◽  
GS Ranga ◽  
A Kumar

2021 ◽  
pp. 104-105
Author(s):  
Deepa Sharnagat ◽  
Vishal Sawant ◽  
Alpana Kondekar

Dengue is a vector-borne disease caused by dengue virus. It has a diverse presentation and usually presents as an asymptomatic, self-limiting disease. Among the unusual presentations, hepatic dysfunction is well reported. Complications of dengue fever can be protean and life-threatening. Dengue may cause bone marrow suppression leading to thrombocytopenia, leukopenia and anemia in acute phase of illness; and increased hematocrit due to capillary leakage, but these changes are self-limiting and require no further investigations and specic treatment. Dengue associated Hemophagocytic lymphohistiocytosis (HLH) is a rare complication of Dengue haemorrhagic fever or Dengue shock syndrome. Diagnosis of secondary HLH (sHLH) due to dengue is usually challenging and delayed as initial clinical symptoms mimic sepsis and systemic inammatory response syndrome (SIRS). Delayed or no treatment of sHLH has a poor outcome. We present an unusual case of classical dengue fever presented as Acute liver failure (ALF) with encephalopathy, later complicated by sHLH.


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