Validation of a quantitative imaging assessment biomarker metric for MRI-estimated proton density fat fraction in a large multi-center clinical trial

Journal of Hepatology ◽

10.1016/s0168-8278(18)31399-0 ◽

2018 ◽

Vol 68 ◽

pp. S571

Author(s):

M. Middleton ◽

W. Henderson ◽

J. Cui ◽

A. Mamidipalli ◽

R. Myers ◽

...

Keyword(s):

Clinical Trial ◽

Quantitative Imaging ◽

Proton Density ◽

Proton Density Fat Fraction ◽

Fat Fraction

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Linearity and Bias of Proton Density Fat Fraction as a Quantitative Imaging Biomarker: A Multicenter, Multiplatform, Multivendor Phantom Study

Radiology ◽

10.1148/radiol.2021202912 ◽

2021 ◽

Vol 298 (3) ◽

pp. 640-651

Author(s):

Houchun H. Hu ◽

Takeshi Yokoo ◽

Mustafa R. Bashir ◽

Claude B. Sirlin ◽

Diego Hernando ◽

...

Keyword(s):

Quantitative Imaging ◽

Phantom Study ◽

Imaging Biomarker ◽

Proton Density ◽

Proton Density Fat Fraction ◽

Quantitative Imaging Biomarker ◽

Fat Fraction

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Hepatic Proton Density Fat Fraction Correlates with Histologic Measures of Steatosis and is Responsive to Change in those Measures in a Multi-Center Nonalcoholic Steatohepatitis Clinical Trial

Gastroenterology ◽

10.1016/s0016-5085(17)33625-9 ◽

2017 ◽

Vol 152 (5) ◽

pp. S1074

Author(s):

Rohit Loomba ◽

Eric Lawitz ◽

Saumya Jayakumar ◽

Parvez S. Mantry ◽

Stephen H. Caldwell ◽

...

Keyword(s):

Clinical Trial ◽

Nonalcoholic Steatohepatitis ◽

Proton Density ◽

Proton Density Fat Fraction ◽

Fat Fraction

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Hepatic proton density fat fraction correlates with histologic measures of steatosis and is responsive to change in those measures in a multi-center nonalcoholic steatohepatitis clinical trial

Journal of Hepatology ◽

10.1016/s0168-8278(17)31805-6 ◽

2017 ◽

Vol 66 (1) ◽

pp. S668 ◽

Cited By ~ 1

Author(s):

M.S. Middleton ◽

E. Lawitz ◽

S. Jayakumar ◽

P. Mantry ◽

S. Caldwell ◽

...

Keyword(s):

Clinical Trial ◽

Nonalcoholic Steatohepatitis ◽

Proton Density ◽

Proton Density Fat Fraction ◽

Fat Fraction

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Responsiveness of controlled attenuation parameter (CAP) and its correlation with magnetic resonance imaging-proton density fat fraction (MRI-PDFF) in a multi-center clinical trial of subjects with nonalcoholic steatohepatitis (NASH)

Journal of Hepatology ◽

10.1016/s0168-8278(18)31386-2 ◽

2018 ◽

Vol 68 ◽

pp. S564

Author(s):

M. Noureddin ◽

Z. Kayali ◽

S. Harrison ◽

P. Ruane ◽

N. Gitlin ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Clinical Trial ◽

Magnetic Resonance ◽

Nonalcoholic Steatohepatitis ◽

Proton Density ◽

Resonance Imaging ◽

Controlled Attenuation Parameter ◽

Proton Density Fat Fraction ◽

Attenuation Parameter ◽

Fat Fraction

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Su1532 - Effect on Accuracy of a Quantitative Imaging Assessment Biomarker Metric for Mri-Estimated Proton Density Fat Fraction

Gastroenterology ◽

10.1016/s0016-5085(18)33873-3 ◽

2018 ◽

Vol 154 (6) ◽

pp. S-1169

Author(s):

Michael S. Middleton ◽

Elhamy Heba ◽

Jennifer Y. Cui ◽

Walter C. Henderson ◽

Adrija Mamidipalli ◽

...

Keyword(s):

Quantitative Imaging ◽

Proton Density ◽

Proton Density Fat Fraction ◽

Fat Fraction

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Inter-reader agreement of magnetic resonance imaging proton density fat fraction and its longitudinal change in a clinical trial of adults with nonalcoholic steatohepatitis

Abdominal Radiology ◽

10.1007/s00261-018-1745-3 ◽

2018 ◽

Vol 44 (2) ◽

pp. 482-492 ◽

Cited By ~ 1

Author(s):

Jonathan C. Hooker ◽

Gavin Hamilton ◽

Charlie C. Park ◽

Steven Liao ◽

Tanya Wolfson ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Clinical Trial ◽

Magnetic Resonance ◽

Nonalcoholic Steatohepatitis ◽

Longitudinal Change ◽

Proton Density ◽

Resonance Imaging ◽

Proton Density Fat Fraction ◽

Fat Fraction

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Magnetic resonance imaging-proton density fat fraction (MRI-PDFF) to predict treatment response on NASH liver biopsy: a secondary analysis of the resmetirom randomized placebo-controlled phase 2 clinical trial

Journal of Hepatology ◽

10.1016/s0168-8278(20)30656-5 ◽

2020 ◽

Vol 73 ◽

pp. S56

Author(s):

Rohit Loomba ◽

Cynthia Guy ◽

Pierre Bedossa ◽

Rebecca Taub ◽

Mustafa Bashir ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Clinical Trial ◽

Secondary Analysis ◽

Proton Density ◽

Phase 2 ◽

Resonance Imaging ◽

Proton Density Fat Fraction ◽

Phase 2 Clinical Trial ◽

Fat Fraction ◽

Predict Treatment Response

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Free‐breathing multitasking multi‐echo MRI for whole‐liver water‐specific T 1 , proton density fat fraction, and quantification

Magnetic Resonance in Medicine ◽

10.1002/mrm.28970 ◽

2021 ◽

Author(s):

Nan Wang ◽

Tianle Cao ◽

Fei Han ◽

Yibin Xie ◽

Xiaodong Zhong ◽

...

Keyword(s):

Free Breathing ◽

Proton Density ◽

Proton Density Fat Fraction ◽

Fat Fraction

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Temperature‐corrected proton density fat fraction estimation using chemical shift‐encoded MRI in phantoms

Magnetic Resonance in Medicine ◽

10.1002/mrm.28669 ◽

2021 ◽

Vol 86 (1) ◽

pp. 69-81 ◽

Cited By ~ 1

Author(s):

Ruvini Navaratna ◽

Ruiyang Zhao ◽

Timothy J. Colgan ◽

Houchun Harry Hu ◽

Mark Bydder ◽

...

Keyword(s):

Chemical Shift ◽

Proton Density ◽

Proton Density Fat Fraction ◽

Fat Fraction

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Repeatability and accuracy of various region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification

Abdominal Radiology ◽

10.1007/s00261-021-02965-5 ◽

2021 ◽

Author(s):

Cheng William Hong ◽

Jennifer Y. Cui ◽

Danielle Batakis ◽

Yang Xu ◽

Tanya Wolfson ◽

...

Keyword(s):

Region Of Interest ◽

Proton Density ◽

Sampling Strategies ◽

Proton Density Fat Fraction ◽

Fat Fraction

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