Quantitative structure-activity relationships in the 8-amino-6,7,8,9-tetrahydro-3H-benz[e]indole ring system. Analysis of serotonin 5-HT1A effects in vivo and in vitro via partial least squares regression

1997 ◽  
Vol 32 (7-8) ◽  
pp. 571-582 ◽  
Author(s):  
L.O. Hansson ◽  
M.D. Ennis ◽  
P Stjernlöf
Keyword(s):  
Partial Least Squares Regression ◽  
System Analysis ◽  
Ring System ◽  
Indole Ring ◽  
Quantitative Structure ◽  
Least Squares Regression ◽  
Structure Activity ◽  
Quantitative Structure Activity Relationships

Quantitative Structure Activity Relationships of Fungicidally Active Triazoles: Analogs and Stereoisomers of Propiconazole and Etaconazole Quantitative Structure Activity Relationships of Fungicidally Active Triazoles: Analogs and Stereoisomers of Propiconazole and Etaconazole

1989 ◽  
Vol 44 (1-2) ◽  
pp. 85-96 ◽  
Author(s):  
E. Ebert ◽  
W. Eckhardt ◽  
K. Jäkel ◽  
D. Sozzi ◽  
C. Vogel ◽  
...  
Keyword(s):  
Fungicidal Activity ◽  
Quantitative Structure ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Quantitative Structure Activity Relationships

Abstract The preparation of the four stereoisomers of propiconazole (TILT®) is described. Their inhibition of the 14α-C-demethylation of the sterol nucleus is examined and compared with the inhibition by the four stereoisomers of etaconazole (SONAX®). The quantitative structure-activity relationships (QSAR) of substituted 1,3-dioxolane-2-yl-methyltriazoles and 1,3-dioxane-2-ylmethyltriazoles on in vivo fungicidal activity are investigated.

Thyroxine analogs. 23. Quantitative structure-activity correlation studies of in vivo and in vitro thyromimetic activities

1977 ◽  
Vol 20 (7) ◽  
pp. 863-880 ◽  
Author(s):  
Stephen W. Dietrich ◽  
Michael B. Bolger ◽  
Peter A. Kollman ◽  
Eugene C. Jorgensen
Keyword(s):  
Quantitative Structure ◽  
Correlation Studies ◽  
Structure Activity
Sign in / Sign up

Export Citation Format

Share Document