Amino acid metabolism in patients with chronic renal failure

1985 ◽  
Vol 4 ◽  
pp. 14-23 ◽  
Author(s):  
A ALVESTRAND
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism

Abnormalities in Amino Acid Metabolism in Patients with Chronic Renal Failure

2015 ◽  
pp. 11-19 ◽  
Author(s):  
Giacomo Deferrari ◽  
Giacomo Garibotto ◽  
Cristina Robaudo ◽  
Stefano Saffioti ◽  
Ernesto Paoletti ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism

Abnormalities in Amino Acid Metabolism in Chronic Renal Failure

2015 ◽  
pp. 169-180 ◽  
Author(s):  
Alberto Tizianello ◽  
Giacomo Deferrari ◽  
Giacomo Garibotto ◽  
Cristina Robaudo ◽  
Stefano Saffioti ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism

Glucose and amino acid metabolism in chronic renal failure: effect of insulin and amino acids

1992 ◽  
Vol 262 (2) ◽  
pp. F168-F176 ◽  
Author(s):  
P. Castellino ◽  
A. Solini ◽  
L. Luzi ◽  
J. G. Barr ◽  
D. J. Smith ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Whole Body ◽  
Glucose Disposal ◽  
Amino Acid Infusion ◽  
Leucine Oxidation ◽  
Control Subjects

The effects of hyperinsulinemia and hyperaminoacidemia on glucose and amino acid metabolism were examined in 16 control and 13 chronic renal failure (CRF) patients under two conditions: 1) euglycemic hyperinsulinemia and 2) amino acid infusion. All studies were performed with continuous indirect calorimetry and [1–14C]leucine infusion. In CRF patients insulin-mediated whole body glucose metabolism was reduced by 35% (4.41 +/- 0.50 vs. 6.76 +/- 0.73 mg.kg-1.min-1, P less than 0.01), primarily due to a decrease in nonoxidative glucose disposal (1.70 +/- 0.70 vs. 4.32 +/- 0.60 mg.kg-1.min-1, P less than 0.01); glucose oxidation was similar in both groups. In the postabsorptive state total leucine turnover (1.56 +/- 0.06 vs. 1.75 +/- 0.06), leucine oxidation (0.25 +/- 0.01 vs. 0.30 +/- 0.01), and nonoxidative leucine disposal (1.29 +/- 0.06 vs. 1.40 +/- 0.07 mumol.kg-1.min-1) were reduced in CRF vs. control subjects (all P less than 0.05). In response to hyperinsulinemia, endogenous leucine flux (index of proteolysis), leucine oxidation, nonoxidative leucine disposal (NOLD) (index of protein synthesis), and net leucine flux into protein were similar in CRF and control subjects. In contrast, the ability of hyperaminoacidemia to enhance NOLD (1.54 +/- 0.11 vs. 2.10 +/- 0.10 mumol.kg-1.min-1, P less than 0.01) and net leucine balance (0.27 +/- 0.05 vs. 0.41 +/- 0.05, P less than 0.05) was reduced in CRF patients.(ABSTRACT TRUNCATED AT 250 WORDS)

Abnormalities in Amino Acid Metabolism in Patients with Chronic Renal Failure

2015 ◽  
pp. 1-10 ◽  
Author(s):  
Alberto Tizianello ◽  
Giacomo Deferrari ◽  
Giacomo Garibotto ◽  
Cristina Robaudo ◽  
Stefano Saffioti ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism

scholarly journals Amino Acid Metabolism in Acute Renal Failure

1974 ◽  
Vol 180 (3) ◽  
pp. 350-355 ◽  
Author(s):  
RONALD M. ABEL ◽  
VIVIAN E. SHIH ◽  
WILLIAM M. ABBOTT ◽  
CLYDE H. BECK ◽  
JOSEPH E. FISCHER
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism

Amino acid metabolism and the liver in renal failure

1980 ◽  
Vol 33 (7) ◽  
pp. 1354-1362 ◽  
Author(s):  
A Tizianello ◽  
G De Ferrari ◽  
G Garibotto ◽  
C Robaudo
Keyword(s):  
Renal Failure ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism
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