Molecular Mechanisms of Thyroid Hormone Action: A Physiologic Perspective

1993 ◽  
Vol 13 (3) ◽  
pp. 543-561 ◽  
Author(s):  
H.L. Schwartz ◽  
K.A. Strait ◽  
J.H. Oppenheimer
Keyword(s):  
Thyroid Hormone ◽  
Molecular Mechanisms ◽  
Hormone Action ◽  
Thyroid Hormone Action

Molecular mechanisms of sex-dependent thyroid hormone action on target tissues

2014 ◽  
Vol 122 (03) ◽  
Author(s):  
H Rakov ◽  
K Engels ◽  
D Zwanziger ◽  
M Renders ◽  
K Brix ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Molecular Mechanisms ◽  
Hormone Action ◽  
Thyroid Hormone Action

Molecular Mechanisms of Thyroid Hormone Action

1993 ◽  
Vol 13 (3) ◽  
pp. 531-541 ◽  
Author(s):  
Allan R. Shepard ◽  
Norman L. Eberhardt
Keyword(s):  
Thyroid Hormone ◽  
Molecular Mechanisms ◽  
Hormone Action ◽  
Thyroid Hormone Action

Physiological and Molecular Basis of Thyroid Hormone Action

2001 ◽  
Vol 81 (3) ◽  
pp. 1097-1142 ◽  
Author(s):  
Paul M. Yen
Keyword(s):  
Thyroid Hormone ◽  
Molecular Mechanisms ◽  
Physiological Function ◽  
Nuclear Hormone Receptor ◽  
Genetically Engineered ◽  
Hormone Action ◽  
Genetically Engineered Mouse Models ◽  
Thyroid Hormone Action ◽  
Tremendous Progress ◽  
Growth Metabolism

Thyroid hormones (THs) play critical roles in the differentiation, growth, metabolism, and physiological function of virtually all tissues. TH binds to receptors that are ligand-regulatable transcription factors belonging to the nuclear hormone receptor superfamily. Tremendous progress has been made recently in our understanding of the molecular mechanisms that underlie TH action. In this review, we present the major advances in our knowledge of the molecular mechanisms of TH action and their implications for TH action in specific tissues, resistance to thyroid hormone syndrome, and genetically engineered mouse models.

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