Evidence that the neuronal nitric oxide synthase inhibitor 7-nitroindazole inhibits monoamine oxidase in the rat: in vivo effects on extracellular striatal dopamine and 3,4-dihydroxyphenylacetic acid

1999 ◽  
Vol 264 (1-3) ◽  
pp. 5-8 ◽  
Author(s):  
Christophe Desvignes ◽  
Lionel Bert ◽  
Laurent Vinet ◽  
Luc Denoroy ◽  
Bernard Renaud ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Monoamine Oxidase ◽  
Neuronal Nitric Oxide Synthase ◽  
Nitric Oxide Synthase Inhibitor ◽  
Dihydroxyphenylacetic Acid ◽  
Synthase Inhibitor ◽  
Oxide Synthase ◽  
In Vivo Effects

scholarly journals Retraction: 7-nitroindazole, a selective neuronal nitric oxide synthase inhibitor in vivo prevents kainate-induced intrahippocampal neurotoxicity. Radenovic L, Selakovic V, Bozic B. Arch Biol Sci. 2005;57(2)75-81. DOI: 10.2298/ABS0502075R

2016 ◽  
Vol 68 (3) ◽  
pp. 691-691
Author(s):  
E Editorial
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Neuronal Nitric Oxide Synthase ◽  
Nitrite Concentration ◽  
Nitric Oxide Synthase Inhibitor ◽  
Retracted Article ◽  
Synthase Inhibitor ◽  
Oxide Synthase ◽  
Font Color

The article: 7-Nitroindazole, a selective neuronal nitric oxide synthase inhibitor in vivo prevents kainate-induced intrahippocampal neurotoxicity. Radenovic L, Selakovic V, Bozic B. Arch Biol Sci. 2005;57(2)75-81, repeats data already published in: 7-Nitroindazole reduces nitrite concentration in rat brain after intrahippocampal kainate-induced seizure. Radenovic L, Vasiljevic I, Selakovic V, Jovanovic M. Comp Biochem Physiol Pt. C. 2003;135 443-50, without any referencing. <br><br><font color="red"><b> Link to the retracted article <u><a href="http://dx.doi.org/10.2298/ABS0502075R">10.2298/ABS0502075R</a></b></u>

scholarly journals 7-nitroindazole, a selective neuronal nitric oxide synthase inhibitore in vivo, prevents kainate-induced intrahippocampal neurotoxicity

2005 ◽  
Vol 57 (2) ◽  
pp. 75-81 ◽  
Author(s):  
Lidija Radenovic ◽  
Vesna Selakovic ◽  
Biljana Bozic
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Neurological Diseases ◽  
Neuronal Nitric Oxide Synthase ◽  
Nitrite Accumulation ◽  
Nitric Oxide Synthase Inhibitor ◽  
Kainic Acid Injection ◽  
Synthase Inhibitor ◽  
Oxide Synthase

We investigated the effects of 7-nitroindazole (7-NI), a selective neuronal nitric oxide synthase inhibitor in vivo, on nitrite concentration after kainic acid injection unilaterally into the CA3 region of the rat hippocampus. The accumulation of nitrite, the stable metabolite of NO, was measured by the Griess reaction at different times in hippocampus, forebrain cortex, striatum, and cerebellum homogenates. 7-nitroindazole can effectively inhibit NO synthesis in rat brain after kainate-induced neurotoxicity and suppressed nitrite accumulation. The present results suggest that neuronal NO synthase inhibitors may be useful in the treatment of neurological diseases in which excitotoxic mechanisms play a role. <br><br><font color="red"><b> This article has been retracted. Link to the retraction <u><a href="http://dx.doi.org/10.2298/ABS160412036E">10.2298/ABS160412036E</a><u></b></font>

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