Metabolic abnormalities of severe, chronic treatment resistant depression post VNS implant

2002 ◽  
Vol 17 ◽  
pp. 112 ◽  
Author(s):  
S. Sheikh ◽  
F. Abuzzahab ◽  
J. Lee ◽  
J. Pardo ◽  
M. Hagen
Keyword(s):  
Chronic Treatment ◽  
Metabolic Abnormalities ◽  
Treatment Resistant Depression ◽  
Treatment Resistant ◽  
Resistant Depression

scholarly journals Vagus nerve stimulation in chronic treatment-resistant depression

2006 ◽  
Vol 189 (3) ◽  
pp. 282-283 ◽  
Author(s):  
Ciaran D. Corcoran ◽  
Philip Thomas ◽  
Jack Phillips ◽  
Veronica O'Keane
Keyword(s):  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Chronic Treatment ◽  
Rating Scale ◽  
Treatment Resistant Depression ◽  
Treatment Resistant ◽  
Remission Rates ◽  
Resistant Depression ◽  
Hamilton Rating Scale

SummaryWe evaluated the efficacy and safety of vagus nerve stimulation therapy in the treatment of 11 patients with chronic treatment-resistant depression. Mood was evaluated at frequent intervals over the year following implantation. All measures of depression, including the Hamilton Rating Scale for Depression reduced significantly. The response and remission rates were 55% and 27% respectively at 1 year. Side-effects were common, and some were severe.

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