Design, synthesis, and structure–Activity relationships of unsubstituted piperazinone-Based transition state factor Xa inhibitors

2003 ◽  
Vol 13 (4) ◽  
pp. 723-728 ◽  
Author(s):  
Wenrong Huang ◽  
Mary Ann Naughton ◽  
Hua Yang ◽  
Ting Su ◽  
Suiko Dam ◽  
...  
Keyword(s):  
Transition State ◽  
Factor Xa ◽  
Factor Xa Inhibitors ◽  
Design Synthesis ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
State Factor

Rational Design, Synthesis, and Structure−Activity Relationships of Novel Factor Xa Inhibitors:  (2-Substituted-4-amidinophenyl)pyruvic and -propionic Acids1

2003 ◽  
Vol 46 (10) ◽  
pp. 1845-1857 ◽  
Author(s):  
Kazuyuki Sagi ◽  
Tadakiyo Nakagawa ◽  
Masahiro Yamanashi ◽  
Shingo Makino ◽  
Mitsuo Takahashi ◽  
...  
Keyword(s):  
Rational Design ◽  
Factor Xa ◽  
Factor Xa Inhibitors ◽  
Design Synthesis ◽  
Structure Activity Relationships ◽  
Structure Activity

Design, synthesis and structure–Activity relationships of benzoxazinone-Based factor Xa inhibitors

2003 ◽  
Vol 13 (3) ◽  
pp. 561-566 ◽  
Author(s):  
Wenrong Huang ◽  
Penglie Zhang ◽  
Jingmei F Zuckett ◽  
Lingyan Wang ◽  
John Woolfrey ◽  
...  
Keyword(s):  
Factor Xa ◽  
Factor Xa Inhibitors ◽  
Design Synthesis ◽  
Structure Activity Relationships ◽  
Structure Activity

Structure–activity relationships of anthranilamide-based factor Xa inhibitors containing piperidinone and pyridinone P4 moieties

2008 ◽  
Vol 18 (9) ◽  
pp. 2845-2849 ◽  
Author(s):  
James R. Corte ◽  
Tianan Fang ◽  
Donald J.P. Pinto ◽  
Wei Han ◽  
Zilun Hu ◽  
...  
Keyword(s):  
Factor Xa ◽  
Factor Xa Inhibitors ◽  
Structure Activity Relationships ◽  
Structure Activity
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