Synthesis and metabotropic glutamate receptor antagonist activity of N1-substituted analogs of 2R,4R-4-aminopyrrolidine-2,4-dicarboxylic acid

Antagonist Activity ◽

Metabotropic Glutamate ◽

ChemInform Abstract: Synthesis and Metabotropic Glutamate Receptor Antagonist Activity of N1-Substituted Analogues of 2R,4R-4-Aminopyrrolidine-2,4-dicarboxylic Acid.

ChemInform ◽

10.1002/chin.199847227 ◽

2010 ◽

Vol 29 (47) ◽

pp. no-no

Author(s):

M. J. VALLI ◽

D. D. SCHOEPP ◽

R. A. WRIGHT ◽

B. G. JOHNSON ◽

A. E. KINGSTON ◽

...

Keyword(s):

Dicarboxylic Acid ◽

Receptor Antagonist ◽

Glutamate Receptor ◽

Antagonist Activity ◽

Metabotropic Glutamate ◽

Clinical studies with the metabotropic glutamate receptor antagonist AFQ056voglurant in adults and adolescents with fragile X syndrome

Neuropsychiatrie de l Enfance et de l Adolescence ◽

10.1016/j.neurenf.2012.04.288 ◽

2012 ◽

Vol 60 (5) ◽

pp. S178

Author(s):

T. Jaecklin ◽

B. Koumaras ◽

A. Angelov ◽

C. Collober ◽

F.N. Hossain ◽

...

Keyword(s):

Receptor Antagonist ◽

Fragile X Syndrome ◽

Glutamate Receptor ◽

Clinical Studies ◽

Fragile X ◽

Metabotropic Glutamate ◽

Effects of the metabotropic glutamate receptor antagonist MCPG on spatial and context-specific learning

Neuropharmacology ◽

10.1016/s0028-3908(96)00101-3 ◽

1996 ◽

Vol 35 (11) ◽

pp. 1557-1565 ◽

Cited By ~ 28

Author(s):

Fabio Bordi ◽

Clara Marcon ◽

Christian Chiamulera ◽

Angelo Reggiani

Keyword(s):

Receptor Antagonist ◽

Glutamate Receptor ◽

Metabotropic Glutamate ◽

Context Specific ◽

Specific Learning ◽

The molecular switch hypothesis fails to explain the inconsistent effects of the metabotropic glutamate receptor antagonist MCPG on long-term potentiation

Brain Research ◽

10.1016/0006-8993(95)00757-h ◽

1995 ◽

Vol 695 (1) ◽

pp. 45-52 ◽

Cited By ~ 33

Author(s):

Mark J. Thomas ◽

Thomas J. O'Dell

Keyword(s):

Receptor Antagonist ◽

Glutamate Receptor ◽

Long Term Potentiation ◽

Molecular Switch ◽

Metabotropic Glutamate ◽

Term Potentiation ◽

Absolute Configuration of (+)-α-Methyl-4-carboxyphenylglycine (MCPG), a Metabotropic Glutamate Receptor Antagonist

Acta Crystallographica Section C Crystal Structure Communications ◽

10.1107/s0108270197003223 ◽

1997 ◽

Vol 53 (7) ◽

pp. 909-911 ◽

Cited By ~ 3

Author(s):

C. Wilson ◽

J. A. K. Howard ◽

D. E. Jane ◽

D. C. Sunter ◽

J. C. Watkins

Keyword(s):

Receptor Antagonist ◽

Glutamate Receptor ◽

Absolute Configuration ◽

Metabotropic Glutamate ◽

AMPA receptor stimulation mediates the antidepressant-like effect of a group II metabotropic glutamate receptor antagonist

Brain Research ◽

10.1016/j.brainres.2005.02.032 ◽

2005 ◽

Vol 1042 (1) ◽

pp. 92-98 ◽

Cited By ~ 100

Author(s):

Jun-ichi Karasawa ◽

Toshiharu Shimazaki ◽

Naoya Kawashima ◽

Shigeyuki Chaki

Keyword(s):

Receptor Antagonist ◽

Glutamate Receptor ◽

Ampa Receptor ◽

Receptor Stimulation ◽

Metabotropic Glutamate ◽

Group Ii ◽

Antinociceptive effect of a group II metabotropic glutamate receptor antagonist in the thalamus of monoarthritic rats

Neuroscience Letters ◽

10.1016/s0304-3940(00)01613-x ◽

2000 ◽

Vol 296 (1) ◽

pp. 25-28 ◽

Cited By ~ 17

Author(s):

Fani Lourenço Neto ◽

José Manuel Castro-Lopes

Keyword(s):

Receptor Antagonist ◽

Glutamate Receptor ◽

Antinociceptive Effect ◽

Metabotropic Glutamate ◽

Group Ii ◽

ChemInform Abstract: (2S,4S)-2-Amino-4-(2,2-diphenylethyl)pentanedioic Acid Selective Group 2 Metabotropic Glutamate Receptor Antagonist.

ChemInform ◽

10.1002/chin.199830227 ◽

2010 ◽

Vol 29 (30) ◽

pp. no-no

Author(s):

A. ESCRIBANO ◽

J. EZQUERRA ◽

C. PEDREGAL ◽

A. RUBIO ◽

B. YRURETAGOYENA ◽

...

Keyword(s):

Receptor Antagonist ◽

Glutamate Receptor ◽

Metabotropic Glutamate ◽

Group 2 ◽

Pentanedioic Acid ◽

Inhibition of long-term potentiation in the dentate gyrus of freely moving rats by the metabotropic glutamate receptor antagonist MCPG

Journal of Neuroscience ◽

10.1523/jneurosci.15-01-00087.1995 ◽

1995 ◽

Vol 15 (1) ◽

pp. 87-98 ◽

Cited By ~ 44

Author(s):

G Riedel ◽

G Casabona ◽

KG Reymann

Keyword(s):

Receptor Antagonist ◽

Glutamate Receptor ◽

Long Term Potentiation ◽

Metabotropic Glutamate ◽

Term Potentiation ◽

Freely Moving ◽

Faculty Opinions recommendation of Regulation of Akt and Wnt signaling by the group II metabotropic glutamate receptor antagonist LY341495 and agonist LY379268.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13357077.14726378 ◽

2011 ◽

Author(s):

Samuel Gandy ◽

Soong Ho Kim

Keyword(s):

Wnt Signaling ◽

Receptor Antagonist ◽

Glutamate Receptor ◽

Metabotropic Glutamate ◽

Group Ii ◽