Sequential follow-up results of catheter invention for coronary artery lesions after Kawasaki disease: quantitative coronary artery. Angiography and intravascular ultrasound imaging

2003 ◽  
Vol 12 (1) ◽  
pp. 91
Author(s):  
M. Ishii ◽  
T. Ueno ◽  
H. Ikeda
Keyword(s):  
Coronary Artery ◽  
Kawasaki Disease ◽  
Intravascular Ultrasound ◽  
Ultrasound Imaging ◽  
Coronary Artery Lesions ◽  
Intravascular Ultrasound Imaging ◽  
Coronary Artery Angiography

LONG-TERM FOLLOW-UP RESULTS OF PERCUTANEOUS CATHETER INTERVENTION FOR CORONARY ARTERY LESIONS AFTER KAWASAKI DISEASE: MULTICENTER COLLABORATIVE STUDY

PEDIATRICS ◽  
2008 ◽  
Vol 121 (Supplement 2) ◽  
pp. S94.1-S94 ◽  
Author(s):  
Masahiro Ishii ◽  
Hiromi Muta ◽  
Yayoi Nakahata ◽  
Syouhei Ogata ◽  
Sumito Kimura ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Kawasaki Disease ◽  
Collaborative Study ◽  
Catheter Intervention ◽  
Coronary Artery Lesions ◽  
Percutaneous Catheter ◽  
Long Term Follow Up

Follow-up study of coronary artery lesions due to Kawasaki disease

1992 ◽  
Vol 1 (1) ◽  
pp. 91
Author(s):  
Yutaka Nakamura ◽  
Yasuo Kuno ◽  
Hatsumi Sugiyama ◽  
Takashi Kuwahara ◽  
Shigehiro Yajima
Keyword(s):  
Coronary Artery ◽  
Kawasaki Disease ◽  
Coronary Artery Lesions ◽  
Follow Up Study

Abstract 2557: The Appraisal-Trial: Evaluating RESTEN-MPTM in Patients with Bare Metal Stent de novo Native Coronary Artery Lesions

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Sebastian Philipp ◽  
Dirk Böse ◽  
Igor Kordish ◽  
Johannes Brachmann ◽  
Klinikum Coburg ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Intravascular Ultrasound ◽  
De Novo ◽  
Neointimal Hyperplasia ◽  
Bare Metal Stent ◽  
Coronary Artery Lesions ◽  
Cardiac Events ◽  
Late Lumen Loss ◽  
Vessel Lumen

Background: Although the use of drug-eluting stents has been shown to limit neointimal hyperplasia, currently available DES may adversely affect re-endothelialization, possibly precipitating late cardiac events. The aim of this study was to evaluate the efficacy and safety of a microbubble delivery of c-myc antisense peptide in preventing restenosis after coronary stenting in de novo stenosis with intravascular ultrasound. Methods: A BMS was implanted in de novo coronary artery lesions (RD ≥ 2.5- ≤4.0mm; TL ≥ 15- ≤ 30mm in length). Serial intravascular ultrasound analysis were performed in 25 lesions. A dose of 16mg RESTEN-MPTM (AVI BioPharma/Global Therapeutics LLC) was intravenously administered after stenting and again 24 hours later. Results: A total of 50 patients were enrolled, 34 in Essen, 13 in Coburg and 3 in Heidelberg. Before stenting, the MLD and length of stenosis was determined by QCA. 18 Patients had a LAD lesion, 21 LCX, 12 RCA. 84% (43/51) of the lesions were either Type B2 or C lesions. At six month follow-up, angiography with a QCA was performed. Generally the neointimal proliferation was minor and open vessel lumen could be demonstrated during follow-up. Of the 30 patients currently studied at six-months in the IVUS sub-study, six patients required TLR. Late lumen loss by QCA was 0.47±0.09mm. Volume stenosis by IVUS was 26 ± 4 %. Generally the neointima proliferation was minor and open vessel lumen could be demonstrated during follow-up. Summary: Microbubble delivery of c-myc antisense seems to be effective in reducing neointimal tissue proliferation without the problem of late stent thrombosis, because the proliferation seems to be attenuated but not fully blocked.

Abstract 192: Long Term Coronary Angiography of Giant Coronary Aneurysms after Kawasaki Disease in Mexican Children

Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Luis M Garrido-Garcia ◽  
Jose L Colin ◽  
Alfredo Bobadilla-Aguirre
Keyword(s):  
Coronary Artery ◽  
Kawasaki Disease ◽  
Coronary Angiography ◽  
Coronary Stenosis ◽  
Unknown Etiology ◽  
Coronary Artery Lesions ◽  
Mexican Children ◽  
Coronary Aneurysms

Kawasaki Disease (KD) is an acute febrile illness characterized by systemic vasculitis of unknown etiology. Coronary artery aneurysms (CAA), is one of the most important aspects of this disease. Some patients with KD develop giant coronary aneurysms (z-score > 10) and coronary stenosis, leading to ischemic heart disease. Objective: To determine the outcome of giant coronary artery lesions caused by KD and the value of coronary angiography in the evaluation and follow-up of coronary artery lesions in Mexican children. Materials and Methods: From our Institutional database, 34 patients (23 men and 11 women) who developed giant aneurysms from 1995 to December 2013 were identified. Information on patient demographics, catheter and surgical interventions, and most recent status was collected from medical records. Results: The average age at onset of KD was 13.5 months, and the median observational period was 70 mo. (5 to 163 mo.). During this period 11 patients showed CAA regression, 21 patients persist with CAA and 2 patients died at follow-up. In 9 patients with persistent giant CAA or coronary stenosis we performed cardiac catheterization to evaluate the coronary anatomy and findings of myocardial ischemia. Coronary bypass was performed to alleviate coronary ischemia in 1 patient, this patient developed dilated cardiomyopathy one year after the surgery and died. The overall survival rate in our series is 97%. Conclusions: Despite being a small series, the long-term survival of patients with KD complicated by giant coronary aneurysms in our center is relatively good. However further research should focus on the indications for and effectiveness of percutaneous and surgical coronary interventions.

Sign in / Sign up

Export Citation Format

Share Document