NATURAL HISTORY OF PORTAL HYPERTENSION IN PATIENTS WITH CIRRHOSIS

2001 ◽  
Vol 5 (3) ◽  
pp. 645-663 ◽  
Author(s):  
Roberto de Franchis ◽  
Massimo Primignani
Keyword(s):  
Portal Hypertension ◽  
Natural History ◽  
History Of

scholarly journals Causes and Management of Non-cirrhotic Portal Hypertension​

2020 ◽  
Vol 22 (12) ◽  
Author(s):  
Stefania Gioia ◽  
Silvia Nardelli ◽  
Lorenzo Ridola ◽  
Oliviero Riggio
Keyword(s):  
Liver Transplantation ◽  
Portal Hypertension ◽  
Natural History ◽  
Portal Vein ◽  
Liver Failure ◽  
Western World ◽  
Vein Thrombosis ◽  
Prevention Of Thrombosis ◽  
Portal Cavernoma ◽  
History Of

Abstract Purpose of the Review Non-cirrhotic portal hypertension (NCPH) includes a heterogeneous group of conditions. The aim of this paper is to make an overview on the denominations, diagnostical features and management of porto-sinusoidal vascular disease (PSVD) and chronic portal vein thrombosis (PVT) being the main causes of NCPH in the Western world. Recent Findings The management of NCPH consists in the treatment of associated diseases and of portal hypertension (PH). PH due to PSVD or PVT is managed similarly to PH due to cirrhosis. TIPS placement and liver transplantation are considerable options in patients with refractory variceal bleeding/ascites and with progressive liver failure. Anticoagulation is a cornerstone both in the treatment of thrombosis in PSVD and in the prevention of thrombosis recurrence in patients with portal cavernoma. Summary Physicians should be aware of the existence of PSVD and chronic PVT and actively search them in particular settings. To now, the management of portal hypertension-related complications in NCPH is the same of those of cirrhosis. Large cooperative studies on the natural history of NCPH are necessary to better define its management.

Portal Hypertension and Variceal Hemorrhage

2015 ◽  
Author(s):  
Amir Qamar
Keyword(s):  
Portal Hypertension ◽  
Natural History ◽  
Esophageal Varices ◽  
Variceal Hemorrhage ◽  
Portal Hypertensive Gastropathy ◽  
Gastric Antral Vascular Ectasia ◽  
Esophageal Variceal ◽  
Gastroesophageal Varices ◽  
Vascular Ectasia ◽  
History Of

Gastrointestinal bleeding in patients with cirrhosis can occur from a number of different causes, including portal hypertension, gastric antral vascular ectasia, and acute variceal hemorrhage. The management of these conditions involves a combined medical and endoscopic approach, with radiologic and surgical therapies restricted to refractory cases. This review covers the natural history of gastroesophageal varices, portal hypertensive gastropathy, and gastric antral vascular ectasia; diagnostic principles; primary and secondary prophylaxis relating to esophageal variceal hemorrhage; and treatment overviews for gastric variceal hemorrhage, portal hypertensive gastropathy, and gastric antral vascular ectasia. Figures show the pathophysiology of complications of cirrhosis, esophageal varices as seen during an upper endoscopic procedure, natural history of esophageal varices in patients with cirrhosis, portal hypertensive gastropathy, gastric antral vascular ectasia, and management principles for acute variceal hemorrhage, esophageal variceal ligation, and gastric varices. Tables list the prevalence of various etiologies of hemorrhage in patients with cirrhosis, current recommendations for follow-up screening and surveillance of varices, sensitivities and specificities of some noninvasive markers, and principles of initial management of acute variceal hemorrhage. This review contains 8 highly rendered figures, 4 tables, and 44 references.

Prevalence, classification and natural history of gastric varices: A long-term follow-up study in 568 portal hypertension patients

Hepatology ◽  
1992 ◽  
Vol 16 (6) ◽  
pp. 1343-1349 ◽  
Author(s):  
Shiv K. Sarin ◽  
Deepak Lahoti ◽  
Sanjay P. Saxena ◽  
Nandguri S. Murthy ◽  
Uday K. Makwana
Keyword(s):  
Portal Hypertension ◽  
Natural History ◽  
Gastric Varices ◽  
Follow Up Study ◽  
Long Term Follow Up ◽  
History Of

The natural history of portal hypertension after transjugular intrahepatic portosystemic shunts

1997 ◽  
Vol 112 (3) ◽  
pp. 889-898 ◽  
Author(s):  
AJ Sanyal ◽  
AM Freedman ◽  
VA Luketic ◽  
PP Purdum ◽  
ML Shiffman ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Natural History ◽  
Portosystemic Shunts ◽  
History Of

scholarly journals Natural history of patients with non cirrhotic portal hypertension: Comparison with patients with compensated cirrhosis

2018 ◽  
Vol 50 (8) ◽  
pp. 839-844 ◽  
Author(s):  
Stefania Gioia ◽  
Silvia Nardelli ◽  
Chiara Pasquale ◽  
Ilaria Pentassuglio ◽  
Valeria Nicoletti ◽  
...  
Keyword(s):  
Portal Hypertension ◽  
Natural History ◽  
Compensated Cirrhosis ◽  
History Of

The Natural History of Portal Hypertensive Gastropathy in Patients with Liver Cirrhosis and Mild Portal Hypertension

2004 ◽  
Vol 99 (10) ◽  
pp. 1959-1965 ◽  
Author(s):  
Manuela Merli ◽  
Giorgia Nicolini ◽  
Stefania Angeloni ◽  
Federica Gentili ◽  
Adolfo Francesco Attili ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hypertension ◽  
Natural History ◽  
Portal Hypertensive Gastropathy ◽  
History Of

The Natural History Of Chronic Liver Disease

2018 ◽  
Author(s):  
Esperance A K Schaefer
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Hypertension ◽  
Liver Disease ◽  
Natural History ◽  
Chronic Liver Disease ◽  
Venous Pressure ◽  
Chronic Liver ◽  
Medical Attention ◽  
Number Of Patients ◽  
History Of

The natural history of chronic liver disease is that of a slowly progressive course, in most cases evolving over the course of years to decades. The rate of progression varies by disease state and comorbid conditions, but fibrosis advances on average by one stage every 7 to 10 years. While the development of fibrosis is reversible when the underlying etiology is successfully treated, a large number of patients present to medical attention once advanced fibrosis has already developed. The ultimate clinical and pathological manifestation of chronic liver disease is cirrhosis. Cirrhosis has long been clinically divided into “compensated” and “decompensated” disease, with an estimated 12-year survival in compensated disease and 2-year survival in decompensated disease. Additional clinical stratifications have been proposed, including a five-stage model progressing from cirrhosis without portal hypertension (hepatic venous pressure gradient below 10 mm Hg) to cirrhosis with portal hypertension, and then cirrhosis complicated by bleeding or other decompensating events. These clinical stages correspond to a step-wise increase in mortality and, with the presence of more than one decompensating event, the five-year mortality approaches 90%. The major complications of cirrhosis include varices with or without hemorrhage, ascites, hepatic encephalopathy, immune dysfunction, renal impairment, and hepatocellular carcinoma. Liver transplantation has provided an avenue to alter the course and outcomes in chronic liver disease, with graft survival rates that reach 80% at 5 years.  This review contains 4 figures, 6 tables and 51 references Key Words: natural history, cirrhosis, mortality, hepatocellular carcinoma, acute-on-chronic liver failure

How is the moral stance related to the intentional stance and group thinking?

2020 ◽  
Vol 43 ◽  
Author(s):  
Hannes Rakoczy
Keyword(s):  
Natural History ◽  
Social Cognitive ◽  
Intentional Stance ◽  
Cognitive Capacities ◽  
Shared Intentionality ◽  
History Of ◽  
Group Thinking ◽  
Moral Stance

Abstract The natural history of our moral stance told here in this commentary reveals the close nexus of morality and basic social-cognitive capacities. Big mysteries about morality thus transform into smaller and more manageable ones. Here, I raise questions regarding the conceptual, ontogenetic, and evolutionary relations of the moral stance to the intentional and group stances and to shared intentionality.

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