Adequacy and safety of buccal misoprostol for cervical preparation prior to termination of second-trimester pregnancy

Background: A transvaginal septum occurs if these two tissue groups do not fuse properly by 5 months of embryonic life. The recommended mode of safe termination for second trimester pregnancy with a diagnosis of high transverse vaginal septum is cervical preparation followed by septostomy and dilation and curettage. Case Summary: A 28 years-old gravida-II Para-I (alive by CS for unknown indication) presented at gestational age 15 weeks plus 6. Hysterotomy was done for an indication of septic inevitable missed second trimester abortion plus presumptive diagnosis of high vaginal septum. Conclusion: According to the case reports that has been reported, the recommended management for safe termination of second trimester pregnancy with a diagnosis of transvaginal septum is good cervical preparation followed by septostomy and dilation and curettage (D&E).

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CERVICAL ADENOCARCINOMA IN SITU DIAGNOSED IN A LATE SECOND TRIMESTER PREGNANCY: A CASE REPORT

10.26226/morressier.5f5634191bffda7af85eb48f ◽

2020 ◽

Author(s):

Mariana Francisca Lira Morais

Keyword(s):

Case Report ◽

Cervical Adenocarcinoma ◽

Adenocarcinoma In Situ ◽

Second Trimester ◽

Trimester Pregnancy ◽

Second Trimester Pregnancy

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A Comparison of Oral Misoprostol With Vaginal Misoprostol Administration in Second-Trimester Pregnancy Termination for Fetal Abnormality

Obstetrics and Gynecology ◽

10.1097/00006250-200306000-00026 ◽

2003 ◽

Vol 101 (6) ◽

pp. 1294-1299

Author(s):

Jan E. Dickinson ◽

Sharon F. Evans

Keyword(s):

Pregnancy Termination ◽

Second Trimester ◽

Fetal Abnormality ◽

Trimester Pregnancy ◽

Oral Misoprostol ◽

Second Trimester Pregnancy ◽

Vaginal Misoprostol

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Patients? acceptance of second-trimester pregnancy termination methods

Obstetrics and Gynecology ◽

10.1016/s0029-7844(02)01856-2 ◽

2002 ◽

Vol 99 (4) ◽

pp. S84

Author(s):

H AKOURY

Keyword(s):

Pregnancy Termination ◽

Second Trimester ◽

Trimester Pregnancy ◽

Second Trimester Pregnancy ◽

Patients Acceptance

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268 Fetal Intracardiac KCL with Second Trimester Pregnancy Termination: A Method to Avoid the Hopeless Resuscitation of the Nonviable, Abnormal Abortus

American Journal of Obstetrics and Gynecology ◽

10.1016/s0002-9378(12)91433-7 ◽

1992 ◽

Vol 166 (1) ◽

pp. 352

Keyword(s):

Pregnancy Termination ◽

Second Trimester ◽

Trimester Pregnancy ◽

Second Trimester Pregnancy

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Against - 3D ultrasound in first and second trimester pregnancy - hype or helpful?

Australasian Journal of Ultrasound in Medicine ◽

10.1002/j.2205-0140.2009.tb00057.x ◽

2009 ◽

Vol 12 (3) ◽

pp. 32-34

Author(s):

Janet I Vaughan

Keyword(s):

3D Ultrasound ◽

Second Trimester ◽

Trimester Pregnancy ◽

Second Trimester Pregnancy

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Misoprostol for Termination of Second Trimester Pregnancy

Journal of Patan Academy of Health Sciences ◽

10.3126/jpahs.v1i1.13010 ◽

2015 ◽

Vol 1 (1) ◽

pp. 16-19

Author(s):

Sarada Duwal Shrestha ◽

Alka Singh ◽

Laxmi RC ◽

Benita Pradhan ◽

Wufei Shah ◽

...

Keyword(s):

Side Effects ◽

Success Rate ◽

Congenital Anomalies ◽

Second Trimester ◽

Plain Language ◽

Fetal Demise ◽

Trimester Pregnancy ◽

Second Trimester Pregnancy ◽

Vaginal Misoprostol ◽

Maternal Side

Introductions: The termination of second trimester pregnancy is challenging due unfavorable cervix. This study evaluate the efficacy and maternal side effects of intravaginal misoprostol for termination of second trimester pregnancy. Methods: During one year period from 15th June 2011 to 14th June 2012, Department of Obstetrics and Gynaecology of Patan Hospital, women admitted for second trimester termination of pregnancy for fetal congenital anomalies and intrauterine fetal demise were studied using the International Federation of Gynaecology and Obstetrics recommended doses of vaginal misoprostol. For congenital anomalies, 400 mcg 3 hourly to a maximum of 5 doses were used. For fetal demise, gestational age of 13-17 weeks received 200 mcg every 6 hourly to a maximum of 4 doses, and 18-26 weeks dose was adjusted to 100 mcg. Main outcome measures included success rate of abortion within 48 hours, induction to delivery interval and maternal side effects. Results: There were 40 patients during study period. Success rate for termination of 2nd trimester pregnancy within 48 hours was 88.8% for congenital anomalies. For fetal demise, success of termination was 90.9% at 13-17 weeks and 100% at 18-26 weeks. Median time from induction to delivery was 26.8 hours for congenital anomalies. For fetal demise, it was 18 hours for 13-17 weeks was and 24 hours at 18 to 26 weeks respectively. Abdominal pain was seen in all doses of misoprostol. Conclusions: Vaginal misoprostol is an effective method for termination of second trimester pregnancy. Plain Language Summary: The study was conducted to see the effectiveness of vaginal misoprostol for termination of second trimester pregnancy. The success rate of termination for congenital abnormality and fetal demise was high. Vaginal misoprostol was an effective method for termination of second trimester pregnancy. DOI: http://dx.doi.org/10.3126/jpahs.v1i1.13010 Journal of Patan Academy of Health Sciences. 2014 Jun;1(1):16-19

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