HER2 status correlation between Circulating Tumor Cells (CTC) and corresponding primary tumor in advanced breast cancer patients (pts)

2008 ◽  
Vol 6 (7) ◽  
pp. 168
Author(s):  
M. Pestrin ◽  
S. Bessi ◽  
M. Truglia ◽  
F. Galardi ◽  
S. Cappadona ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Advanced Breast Cancer ◽  
Cancer Patients ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Primary Tumor ◽  
Advanced Breast ◽  
Her2 Status ◽  
Breast Cancer Patients

Changes of HER2 Status in Circulating Tumor Cells Compared With the Primary Tumor During Treatment for Advanced Breast Cancer

2010 ◽  
Vol 10 (5) ◽  
pp. 392-397 ◽  
Author(s):  
Elisabetta Munzone ◽  
Franco Nolé ◽  
Aron Goldhirsch ◽  
Edoardo Botteri ◽  
Angela Esposito ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Advanced Breast Cancer ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Primary Tumor ◽  
Advanced Breast ◽  
Her2 Status

Comparison of HER2 status between primary tumor and disseminated tumor cells in␣primary breast cancer patients

2006 ◽  
Vol 98 (2) ◽  
pp. 179-184 ◽  
Author(s):  
Erich F. Solomayer ◽  
Sven Becker ◽  
Graziella Pergola-Becker ◽  
Robert Bachmann ◽  
Bernhard Krämer ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Tumor Cells ◽  
Primary Tumor ◽  
Primary Breast Cancer ◽  
Disseminated Tumor Cells ◽  
Her2 Status ◽  
Breast Cancer Patients

scholarly journals Circulating Tumor Cells in Breast Cancer Patients: An Evolving Role in Patient Prognosis and Disease Progression

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Holly Graves ◽  
Brian J. Czerniecki
Keyword(s):  
Breast Cancer ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Early Breast Cancer ◽  
Primary Tumor ◽  
Metastatic Breast ◽  
Her2 Status ◽  
Breast Cancer Patients ◽  
Neoplastic Process

In this paper, we examine the role of circulating tumor cells (CTCs) in breast cancer. CTCs are tumor cells present in the peripheral blood. They are found in many different carcinomas but are not present in patients with benign disease. Recent advances in theories regarding metastasis support the role of early release of tumor cells in the neoplastic process. Furthermore, it has been found that phenotypic variation exists between the primary tumor and CTCs. Of particular interest is the incongruency found between primary tumor and CTC HER2 status in both metastatic and early breast cancer. Overall, CTCs have been shown to be a poor prognostic marker in metastatic breast cancer. CTCs in early breast cancer are not as well studied, however, several studies suggest that the presence of CTCs in early breast cancer may also suggest a poorer prognosis. Studies are currently underway looking at the use of CTC level monitoring in order to guide changes in therapy.

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