Safety and immunogenicity of the rVSV∆G-ZEBOV-GP Ebola virus vaccine candidate in healthy adults: a phase 1b randomised, multicentre, double-blind, placebo-controlled, dose-response study

D Gray Heppner; Tracy L Kemp; Brian K Martin; William J Ramsey; Richard Nichols; Emily J Dasen; Charles J Link; Rituparna Das; Zhi Jin Xu; Eric A Sheldon; Teresa A Nowak; Thomas P Monath; DG Heppner; TL Kemp; BK Martin; WJ Ramsey; R Nichols; EJ Dasen; J Fusco; J Crowell; C Link; J Creager; TP Monath; R Das; ZJ Xu; R Klein; T Nowak; E Gerstenberger; R Bliss; EA Sheldon; RA Feldman; Brandon J Essink; WB Smith; L Chu; WM Seger; J Saleh; JL Borders; M Adams

doi:10.1016/s1473-3099(17)30313-4

Safety and immunogenicity of the rVSV∆G-ZEBOV-GP Ebola virus vaccine candidate in healthy adults: a phase 1b randomised, multicentre, double-blind, placebo-controlled, dose-response study

The Lancet Infectious Diseases ◽

10.1016/s1473-3099(17)30313-4 ◽

2017 ◽

Vol 17 (8) ◽

pp. 854-866 ◽

Cited By ~ 51

Author(s):

D Gray Heppner ◽

Tracy L Kemp ◽

Brian K Martin ◽

William J Ramsey ◽

Richard Nichols ◽

...

Keyword(s):

Virus Vaccine ◽

Dose Response ◽

Ebola Virus ◽

Vaccine Candidate ◽

Healthy Adults ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 1B ◽

Dose Response Study

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Use of ChAd3-EBO-Z Ebola virus vaccine in Malian and US adults, and boosting of Malian adults with MVA-BN-Filo: a phase 1, single-blind, randomised trial, a phase 1b, open-label and double-blind, dose-escalation trial, and a nested, randomised, double-blind, placebo-controlled trial

The Lancet Infectious Diseases ◽

10.1016/s1473-3099(15)00362-x ◽

2016 ◽

Vol 16 (1) ◽

pp. 31-42 ◽

Cited By ~ 120

Author(s):

Milagritos D Tapia ◽

Samba O Sow ◽

Kirsten E Lyke ◽

Fadima Cheick Haidara ◽

Fatoumata Diallo ◽

...

Keyword(s):

Virus Vaccine ◽

Ebola Virus ◽

Controlled Trial ◽

Phase 1 ◽

Randomised Trial ◽

Open Label ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 1B ◽

Single Blind

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Safety and immunogenicity of a highly attenuated rVSVN4CT1-EBOVGP1 Ebola virus vaccine: a randomised, double-blind, placebo-controlled, phase 1 clinical trial

The Lancet Infectious Diseases ◽

10.1016/s1473-3099(19)30614-0 ◽

2020 ◽

Vol 20 (4) ◽

pp. 455-466 ◽

Cited By ~ 3

Author(s):

David K Clarke ◽

Rong Xu ◽

Demetrius Matassov ◽

Theresa E Latham ◽

Ayuko Ota-Setlik ◽

...

Keyword(s):

Clinical Trial ◽

Virus Vaccine ◽

Ebola Virus ◽

Phase 1 ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 1 Clinical Trial

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A Randomized, Double-Blind, Placebo-Controlled, Dose-Response Study of the Analgesic Effect of Lornoxicam After Surgical Removal of Mandibular Third Molars

The Journal of Clinical Pharmacology ◽

10.1002/j.1552-4604.1995.tb05018.x ◽

1995 ◽

Vol 35 (6) ◽

pp. 606-614 ◽

Cited By ~ 26

Author(s):

Sven E. Nørholt ◽

Steen Sindet-Pedersen ◽

Christine Bugge ◽

Poul E. Branebjerg ◽

Bjarne K. Ersbøll ◽

...

Keyword(s):

Dose Response ◽

Analgesic Effect ◽

Surgical Removal ◽

Third Molars ◽

Double Blind ◽

Double Blind Placebo ◽

Mandibular Third Molars ◽

Dose Response Study

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Dose-related cardiac electrophysiological effects of intravenous magnesium. A double-blind placebo-controlled dose-response study in patients with paroxysmal supraventricular tachycardia

EP Europace ◽

10.1053/eupc.2000.0123 ◽

2000 ◽

Vol 2 (4) ◽

pp. 320-326 ◽

Cited By ~ 15

Author(s):

E Christiansen

Keyword(s):

Supraventricular Tachycardia ◽

Dose Response ◽

Paroxysmal Supraventricular Tachycardia ◽

Double Blind ◽

Double Blind Placebo ◽

Intravenous Magnesium ◽

Dose Response Study ◽

Electrophysiological Effects

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Clinical trial: the efficacy and tolerability of velusetrag, a selective 5-HT4 agonist with high intrinsic activity, in chronic idiopathic constipation - a 4-week, randomized, double-blind, placebo-controlled, dose-response study

Alimentary Pharmacology & Therapeutics ◽

10.1111/j.1365-2036.2010.04456.x ◽

2010 ◽

Vol 32 (9) ◽

pp. 1102-1112 ◽

Cited By ~ 66

Author(s):

M. Goldberg ◽

Y.-P. Li ◽

J. F. Johanson ◽

A. W. Mangel ◽

M. Kitt ◽

...

Keyword(s):

Clinical Trial ◽

Dose Response ◽

Intrinsic Activity ◽

Double Blind ◽

Idiopathic Constipation ◽

Double Blind Placebo ◽

Chronic Idiopathic Constipation ◽

Dose Response Study

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An open-label extension study following the HRM4396B/3001 study (a double-blind, placebo-controlled, parallel arms, dose response study of two doses of HMR4396 versus placebo for anaemia in subjects treated with chemotherapy)

http://isrctn.org/> ◽

10.1186/isrctn41606826 ◽

2013 ◽

Author(s):

Chris Freitag

Keyword(s):

Dose Response ◽

Extension Study ◽

Open Label ◽

Double Blind ◽

Double Blind Placebo ◽

Open Label Extension ◽

Dose Response Study

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A Randomized, Double-Blind, Placebo-Controlled, Dose-Response Study to Assess the Pharmacokinetics, Efficacy, and Safety of Gabapentin Enacarbil in Subjects With Restless Legs Syndrome

Clinical Neuropharmacology ◽

10.1097/wnf.0b013e318259eac8 ◽

2012 ◽

Vol 35 (4) ◽

pp. 165-173 ◽

Cited By ~ 25

Author(s):

Ritu Lal ◽

Aaron Ellenbogen ◽

Dan Chen ◽

Katie Zomorodi ◽

Harisha Atluri ◽

...

Keyword(s):

Dose Response ◽

Restless Legs Syndrome ◽

Efficacy And Safety ◽

Gabapentin Enacarbil ◽

Double Blind ◽

Double Blind Placebo ◽

Restless Legs ◽

Dose Response Study

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Efficacy and tolerability of sumanirole in restless legs syndrome: A phase II, randomized, double-blind, placebo-controlled, dose–response study

Sleep Medicine ◽

10.1016/j.sleep.2006.05.018 ◽

2007 ◽

Vol 8 (2) ◽

pp. 119-127 ◽

Cited By ~ 12

Author(s):

Diego Garcia-Borreguero ◽

John Winkelman ◽

Alieu Adams ◽

Amanda Ellis ◽

Mark Morris ◽

...

Keyword(s):

Phase Ii ◽

Dose Response ◽

Restless Legs Syndrome ◽

Double Blind ◽

Double Blind Placebo ◽

Restless Legs ◽

Dose Response Study

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Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials

The Lancet ◽

10.1016/s0140-6736(17)33106-9 ◽

2018 ◽

Vol 391 (10120) ◽

pp. 563-571 ◽

Cited By ~ 100

Author(s):

Kayvon Modjarrad ◽

Leyi Lin ◽

Sarah L George ◽

Kathryn E Stephenson ◽

Kenneth H Eckels ◽

...

Keyword(s):

Clinical Trials ◽

Virus Vaccine ◽

Zika Virus ◽

Vaccine Candidate ◽

Phase 1 ◽

Controlled Clinical Trials ◽

Double Blind ◽

Double Blind Placebo

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Double-blind placebo-controlled dose-response study of immunotherapy with standardized cat extract

Journal of Allergy and Clinical Immunology ◽

10.1016/s0091-6749(02)81638-4 ◽

2002 ◽

Vol 109 (1) ◽

pp. S170-S170

Author(s):

Penelope A Ewbank ◽

Jacquelyn Allwein ◽

Karrie Sanders ◽

James R Murphy ◽

Lori Silveira ◽

...

Keyword(s):

Dose Response ◽

Double Blind ◽

Double Blind Placebo ◽

Dose Response Study

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