Abstract #288 Efficacy of Canagliflozin 300 Mg in Overweight and Obese Type 2 Diabetes Mellitus Patients in a Real World Setting

2018 ◽  
Vol 24 ◽  
pp. 76-77
Author(s):  
Pankaj Aneja ◽  
Kunal Aneja ◽  
Gaurav Bhalla ◽  
Navneet Wadhwa

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 2220-PUB
Author(s):  
JUAN J. GORGOJO-MARTINEZ ◽  
MANUEL A. GARGALLO-FERNANDEZ ◽  
ALBA GALDON ◽  
TERESA ANTÓN-BRAVO ◽  
MIGUEL BRITO-SANFIEL ◽  
...  






2015 ◽  
Vol 18 (3) ◽  
pp. A57 ◽  
Author(s):  
P. Lefebvre ◽  
D. Pilon ◽  
M. Robitaille ◽  
M. Lafeuille ◽  
W. Chow ◽  
...  


Author(s):  
Melanie Nana ◽  
Sacha Moore ◽  
Riyanath Loganathan ◽  
Victoria Williams ◽  
Mohammad Rahman ◽  
...  

Introduction: There is a paucity of evidence regarding the efficacy of a very low-calorie diet (VLCD) in the real-world setting. We evaluated outcomes in patients with type 2 diabetes mellitus (T2DM) who underwent VLCD. Methods: This retrospective observational study included all patients who had undergone VLCD from 2014 to 2017 (n=61). The VLCD consisted of an eight-week 800 kcal/day dietary restriction. Metabolic parameters and medications were recorded at baseline, immediately post-VLCD and at 6 and 12 months. Results: There was a significant reduction in weight of 9.96 kg (p<0.001) immediately post-VLCD, with net weight loss sustained to 12 months (p<0.05). There was a significant reduction in body mass index (BMI) sustained to 12 months (p<0.05). Paired HbA1c data were available for 38 patients. There was a significant reduction in HbA1c of 13.29 mmol/mol immediately post-VLCD (p<0.001), however no significant reduction was observed at 12 months (p>0.05). 78.7% patients had a reduction in T2DM medication burden post-VLCD, sustained in 44.3% of patients at 12 months. Analysis of patients with T2DM diagnosis duration >6 years demonstrated statistically significant weight loss sustained to 12 months (p<0.001). Conclusion: Our results demonstrate sustained reduction in BMI and weight, reduction in medication burden and temporary reduction in HbA1c in patients with T2DM undertaking a VLCD in the real-world setting





2018 ◽  
Vol 59 (5) ◽  
pp. 251-256 ◽  
Author(s):  
YL Shao ◽  
KH Yee ◽  
SK, Koh ◽  
YF Wong ◽  
LY Yeoh ◽  
...  


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