Displacement and Nonlinear Chromatographic Techniques in the Investigation of Interaction of Noncompetitive Inhibitors with an Immobilized α3β4 Nicotinic Acetylcholine Receptor Liquid Chromatographic Stationary Phase

Krzysztof Jozwiak; Jun Haginaka; Ruin Moaddel; Irving W. Wainer

doi:10.1021/ac0202029

Displacement and Nonlinear Chromatographic Techniques in the Investigation of Interaction of Noncompetitive Inhibitors with an Immobilized α3β4 Nicotinic Acetylcholine Receptor Liquid Chromatographic Stationary Phase

Analytical Chemistry ◽

10.1021/ac0202029 ◽

2002 ◽

Vol 74 (18) ◽

pp. 4618-4624 ◽

Cited By ~ 56

Author(s):

Krzysztof Jozwiak ◽

Jun Haginaka ◽

Ruin Moaddel ◽

Irving W. Wainer

Keyword(s):

Stationary Phase ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Chromatographic Techniques ◽

Liquid Chromatographic ◽

Noncompetitive Inhibitors

Multidimensional on-line screening for ligands to the α3β4 neuronal nicotinic acetylcholine receptor using an immobilized nicotinic receptor liquid chromatographic stationary phase

Journal of Chromatography B ◽

10.1016/s1570-0232(02)00070-3 ◽

2002 ◽

Vol 772 (1) ◽

pp. 155-161 ◽

Cited By ~ 19

Author(s):

Michael T. Baynham ◽

Sharvil Patel ◽

Ruin Moaddel ◽

Irving W. Wainer

Keyword(s):

Stationary Phase ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Nicotinic Receptor ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

On Line ◽

Liquid Chromatographic

Reversing the Action of Noncompetitive Inhibitors (MK-801 and Cocaine) on a Protein (Nicotinic Acetylcholine Receptor)-Mediated Reaction†

Biochemistry ◽

10.1021/bi020677u ◽

2003 ◽

Vol 42 (20) ◽

pp. 6106-6114 ◽

Cited By ~ 9

Author(s):

George P. Hess ◽

Armanda M. Gameiro ◽

Ryan C. Schoenfeld ◽

Yongli Chen ◽

Henning Ulrich ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Mk 801 ◽

Noncompetitive Inhibitors

Muscle-type nicotinic acetylcholine receptor delta subunit determines sensitivity to noncompetitive inhibitors, while gamma subunit regulates divalent permeability

Neuropharmacology ◽

10.1016/s0028-3908(96)00103-7 ◽

1996 ◽

Vol 35 (11) ◽

pp. 1547-1556 ◽

Cited By ~ 22

Author(s):

Michael M Francis ◽

Roger L Papke

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Muscle Type ◽

Nicotinic Acetylcholine ◽

Gamma Subunit ◽

Delta Subunit ◽

Noncompetitive Inhibitors

Diterpenoids from caribbean gorgonians act as noncompetitive inhibitors of the nicotinic acetylcholine receptor

Cellular and Molecular Neurobiology ◽

10.1007/bf00735367 ◽

1993 ◽

Vol 13 (2) ◽

pp. 99-110 ◽

Cited By ~ 15

Author(s):

Vesna A. Eterović ◽

Richard M. Hann ◽

P. A. Ferchmin ◽

Abimael D. Rodriguez ◽

Lian Li ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Noncompetitive Inhibitors

Liquid chromatographic studies with immobilized neuronal nicotinic acetylcholine receptor stationary phases: effects of receptor subtypes, pH and ionic strength on drug–receptor interactions

Journal of Chromatography B Biomedical Sciences and Applications ◽

10.1016/s0378-4347(98)00579-9 ◽

1999 ◽

Vol 724 (1) ◽

pp. 65-72 ◽

Cited By ~ 30

Author(s):

Irving W Wainer ◽

Yanxiao Zhang ◽

Yingxian Xiao ◽

Kenneth J Kellar

Keyword(s):

Ionic Strength ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Stationary Phases ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Receptor Subtypes ◽

Nicotinic Acetylcholine ◽

Receptor Interactions ◽

Drug Receptor ◽

Liquid Chromatographic

Interaction of Noncompetitive Inhibitors with an Immobilized α3β4 Nicotinic Acetylcholine Receptor Investigated by Affinity Chromatography, Quantitative−Structure Activity Relationship Analysis, and Molecular Docking

Journal of Medicinal Chemistry ◽

10.1021/jm0400707 ◽

2004 ◽

Vol 47 (16) ◽

pp. 4008-4021 ◽

Cited By ~ 42

Author(s):

Krzysztof Jozwiak ◽

Sarangan Ravichandran ◽

Jack R. Collins ◽

Irving W. Wainer

Keyword(s):

Molecular Docking ◽

Affinity Chromatography ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Quantitative Structure Activity Relationship ◽

Quantitative Structure ◽

Nicotinic Acetylcholine ◽

Relationship Analysis ◽

Structure Activity ◽

Noncompetitive Inhibitors

Interaction of Noncompetitive Inhibitors with the α3β2 Nicotinic Acetylcholine Receptor Investigated by Affinity Chromatography and Molecular Docking

Journal of Medicinal Chemistry ◽

10.1021/jm070784s ◽

2007 ◽

Vol 50 (24) ◽

pp. 6279-6283 ◽

Cited By ~ 14

Author(s):

Krzysztof Jozwiak ◽

Sarangan Ravichandran ◽

Jack R. Collins ◽

Ruin Moaddel ◽

Irving W. Wainer

Keyword(s):

Molecular Docking ◽

Affinity Chromatography ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Noncompetitive Inhibitors

Channel permeant cations compete selectively with noncompetitive inhibitors of the nicotinic acetylcholine receptor.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)55356-4 ◽

1991 ◽

Vol 266 (25) ◽

pp. 16691-16698

Author(s):

J.M. Herz ◽

S.J. Kolb ◽

T. Erlinger ◽

E. Schmid

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Noncompetitive Inhibitors

Efficacy of Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation: A Randomized Controlled Trial

Yearbook of Pulmonary Disease ◽

10.1016/s8756-3452(08)70598-x ◽

2008 ◽

Vol 2008 ◽

pp. 109-110

Author(s):

L.T. Tanoue

Keyword(s):

Randomized Controlled Trial ◽

Smoking Cessation ◽

Sustained Release ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Partial Agonist ◽

Controlled Trial ◽

Nicotinic Acetylcholine ◽

Randomized Controlled

Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Sustained-Release Bupropion and Placebo for Smoking Cessation: A Randomized Controlled Trial

Yearbook of Medicine ◽

10.1016/s0084-3873(08)70096-8 ◽

2007 ◽

Vol 2007 ◽

pp. 143-145

Author(s):

N.H. Hanna

Keyword(s):

Randomized Controlled Trial ◽

Smoking Cessation ◽

Sustained Release ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Partial Agonist ◽

Controlled Trial ◽

Nicotinic Acetylcholine ◽

Randomized Controlled