Collision-Induced Dissociation Spectra Obtained by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Using a13C,15N-Doubly Depleted Protein

1998 ◽  
Vol 70 (15) ◽  
pp. 3333-3336 ◽  
Author(s):  
Satoko Akashi ◽  
Koji Takio ◽  
Hiroshi Matsui ◽  
Shin-ichi Tate ◽  
Masatsune Kainosho
Keyword(s):  
Mass Spectrometry ◽  
Fourier Transform ◽  
Cyclotron Resonance ◽  
Collision Induced Dissociation ◽  
Ion Cyclotron Resonance ◽  
Ion Cyclotron

An Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Study of 1,6-Methano[60]Fullerene-61,61-Dicarboxylic Acid

2000 ◽  
Vol 6 (2) ◽  
pp. 161-168 ◽  
Author(s):  
Rui Zhang ◽  
Keith J. Fisher ◽  
Derek R. Smith ◽  
Gary D. Willett ◽  
J. Barrie Peel ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Fourier Transform ◽  
Dicarboxylic Acid ◽  
Electrospray Ionization ◽  
Cyclotron Resonance ◽  
Collision Induced Dissociation ◽  
Ion Cyclotron Resonance ◽  
Molecular Anion ◽  
Electrospray Ionization Fourier Transform ◽  
Ion Cyclotron

1,6-Methano[60]fullerene-61,61-dicarboxylic acid was studied by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. The deprotonated molecule, C60C(COOH)COO−, and the decarboxylated molecular anion C60CHCOO− were observed. Gas-phase ion–molecule reactions occurred when the ion accumulation time in an external rf/dc hexapole ion trap was extended. Cluster ions of the type [C60CHCOOH] n[C60CHCOO]− ( n = 1–2) were observed. Multiply-charged anions were observed for the dimer [C60CHCOOH][C60CHCOO]−. Collision-induced dissociation in the ion cyclotron resonance cell showed that C60C(COOH)COO− dissociated through the loss of two CO2 groups, with further fragmentation to produce C60−. A similar fragmentation pathway was also observed with capillary/skimmer collision-induced dissociation during the electrospray process. Semi-empirical calculations using the AM1 approximation with the MOPAC program have been performed on most of the neutral and ionic species related to this compound. Energy differences and charge distributions have been obtained for the possible geometry structures for these species.

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