Helix–Coil Transition at a Glycine Following a Nascent α-Helix: A Synergetic Guidance Mechanism for Helix Growth

2020 ◽  
Vol 124 (37) ◽  
pp. 7478-7490
Author(s):  
Sunit Pal ◽  
Shreya Banerjee ◽  
Erode N. Prabhakaran
Keyword(s):  
Coil Transition ◽  
Α Helix

α-Helix-to-random-coil transition of two-chain, coiled coils. Theory and experiments for thermal denaturation of α-tropomyosin at acidic pH

1983 ◽  
Vol 16 (3) ◽  
pp. 462-465 ◽  
Author(s):  
Marilyn Emerson Holtzer ◽  
Alfred Holtzer ◽  
Jeffrey Skolnick
Keyword(s):  
Thermal Denaturation ◽  
Coiled Coils ◽  
Random Coil ◽  
Acidic Ph ◽  
Coil Transition ◽  
Α Helix ◽  
Theory And Experiments

CONFORMATION AND PHASE TRANSITION OF POLY-GLUTAMINE

2006 ◽  
Vol 17 (02) ◽  
pp. 235-246 ◽  
Author(s):  
GÖKHAN GÖKOĞLU ◽  
TARIK ÇELİK
Keyword(s):  
Low Temperatures ◽  
Low Energy ◽  
Random Coil ◽  
Polyglutamine Diseases ◽  
Aggregate Formation ◽  
Two Phase ◽  
Coil Transition ◽  
Energy Stable ◽  
Α Helix ◽  
Β Sheet

In order to provide insights into the misfolding mechanism and the subsequent aggregate formation which cause what are known as the neurodegenerative polyglutamine diseases, we have simulated a 10-residue polyglutamine (poly-Q) chain in vacuum and in solvent by multicanonical method, which enabled us to study the system in a wide temperature range and discuss thermodynamic properties. It is understood that the system in vacuum shows two phase transitions, first of them occur at high temperature that is the well-known helix-coil transition and the second one is a solid-solid transition. However, the poly-Q chain in solvent is in a random coil state at higher temperatures, goes through a conformational change at T = 200 K and assumes predominantly a mixture of anti-parallel β-sheet and α-helix structures at low temperatures. One-residue glutamine dipeptide is also simulated and low-energy stable conformations are identified.

α-Helix-to-random-coil transition of two-chain, coiled coils. Experiments on the thermal denaturation of α-tropomyosin and β-tropomyosin

1984 ◽  
Vol 17 (11) ◽  
pp. 2445-2447 ◽  
Author(s):  
Lori L. Isom ◽  
Marilyn Emerson Holtzer ◽  
Alfred Holtzer
Keyword(s):  
Thermal Denaturation ◽  
Coiled Coils ◽  
Random Coil ◽  
Coil Transition ◽  
Α Helix

Theory of α-helix-to-random-coil transition of two-chain, coiled coils. Application of the augmented theory to thermal denaturation of ββ tropomyosin

1986 ◽  
Vol 19 (6) ◽  
pp. 1769-1770 ◽  
Author(s):  
Alfred Holtzer ◽  
Jeffrey Skolnick
Keyword(s):  
Thermal Denaturation ◽  
Coiled Coils ◽  
Random Coil ◽  
Coil Transition ◽  
Α Helix

Crossbridge release and α-helix-coil transition in myosin and rod minifilaments

1983 ◽  
Vol 169 (2) ◽  
pp. 455-468 ◽  
Author(s):  
Dianne Applegate ◽  
Emil Reisler
Keyword(s):  
Coil Transition ◽  
Α Helix

Investigation of the α‐Helix—Random‐Coil Transition in Polyglutamic Acid by Slow Neutron Scattering

1966 ◽  
Vol 44 (8) ◽  
pp. 3127-3128 ◽  
Author(s):  
H. Boutin ◽  
W. L. Whittemore
Keyword(s):  
Neutron Scattering ◽  
Slow Neutron ◽  
Random Coil ◽  
Polyglutamic Acid ◽  
Coil Transition ◽  
Α Helix

Thermodynamics of the α-helix-coil transition of amphipathic peptides in a membrane environment: implications for the peptide-membrane binding equilibrium 1 1Edited by W. Baumeister

1999 ◽  
Vol 294 (3) ◽  
pp. 785-794 ◽  
Author(s):  
Torsten Wieprecht ◽  
Ognjan Apostolov ◽  
Michael Beyermann ◽  
Joachim Seelig
Keyword(s):  
Membrane Binding ◽  
Amphipathic Peptides ◽  
Coil Transition ◽  
Α Helix

α-Helix-to-random coil transition of two-chain, coiled coils. Theory and experiments for thermal denaturation of α-tropomyosin

1983 ◽  
Vol 16 (2) ◽  
pp. 173-180 ◽  
Author(s):  
Marilyn Emerson Holtzer ◽  
Alfred Holtzer ◽  
Jeffrey Skolnick
Keyword(s):  
Thermal Denaturation ◽  
Coiled Coils ◽  
Random Coil ◽  
Coil Transition ◽  
Α Helix ◽  
Theory And Experiments

scholarly journals Stabilization of proteins by rational design of α-helix stability using helix/coil transition theory

1996 ◽  
Vol 1 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Virtudes Villegas ◽  
Ana Rosa Viguera ◽  
F Xavier Avilés ◽  
Luis Serrano
Keyword(s):  
Rational Design ◽  
Transition Theory ◽  
Coil Transition ◽  
Helix Stability ◽  
Α Helix

Intramolecular α-helix-β-structure-random coil transition in polypeptides

1982 ◽  
Vol 16 (4) ◽  
pp. 275-285 ◽  
Author(s):  
Hiromitsu Wakana ◽  
Takao Shigaki ◽  
Nobuhiko Saitô
Keyword(s):  
Random Coil ◽  
Coil Transition ◽  
Α Helix
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