Development and Characterization of Nanoembedded Microparticles for Pulmonary Delivery of Antitubercular Drugs against Experimental Tuberculosis

2015 ◽  
Vol 12 (11) ◽  
pp. 3839-3850 ◽  
Author(s):  
Amit Kumar Goyal ◽  
Tarun Garg ◽  
Goutam Rath ◽  
Umesh Datta Gupta ◽  
Pushpa Gupta
Keyword(s):  
Pulmonary Delivery ◽  
Experimental Tuberculosis ◽  
Antitubercular Drugs

scholarly journals Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 5. Oseltamivir Carboxylate

2016 ◽  
Vol 60 (8) ◽  
pp. 5085-5087 ◽  
Author(s):  
Danilo Cesar Galindo Bedor ◽  
Sandrine Marchand ◽  
Isabelle Lamarche ◽  
Julian Laroche ◽  
Davi Pereira de Santana ◽  
...  
Keyword(s):  
Antimicrobial Agents ◽  
Area Under The Curve ◽  
Pulmonary Delivery ◽  
Epithelial Lining ◽  
Oseltamivir Carboxylate ◽  
Epithelial Lining Fluid

ABSTRACTThe aim of this study was to determine the biopharmaceutical characteristics of oseltamivir carboxylate (OC) after pulmonary delivery. After OC bolus and intratracheal nebulization (NEB) in rats, blood was collected and bronchoalveolar lavages (BALs) were performed. Epithelial lining fluid (ELF) concentrations were estimated from BAL fluid. The area under the curve (AUC) ratio for ELF to plasma was 842 times higher after NEB than after intravenous (i.v.) administration, indicating that OC nebulization offers a biopharmaceutical advantage over i.v. administration.

Pulmonary delivery of antitubercular drugs using spray-dried lipid–polymer hybrid nanoparticles

2015 ◽  
Vol 44 (6) ◽  
pp. 1544-1555 ◽  
Author(s):  
Ankur Bhardwaj ◽  
Shuchi Mehta ◽  
Shailendra Yadav ◽  
Sudheer K. Singh ◽  
Anne Grobler ◽  
...  
Keyword(s):  
Pulmonary Delivery ◽  
Hybrid Nanoparticles ◽  
Antitubercular Drugs ◽  
Polymer Hybrid ◽  
Spray Dried

Synthesis, Optimization, and Characterization of Camptothecin-Loaded Acetalated Dextran Porous Microparticles for Pulmonary Delivery

2012 ◽  
Vol 9 (2) ◽  
pp. 290-298 ◽  
Author(s):  
Samantha A. Meenach ◽  
Yu Jeong Kim ◽  
Kevin J. Kauffman ◽  
Naveen Kanthamneni ◽  
Eric M. Bachelder ◽  
...  
Keyword(s):  
Pulmonary Delivery ◽  
Porous Microparticles

Formulation and Characterization of Polysaccharide Microparticles for Pulmonary Delivery of Sodium Cromoglycate

2016 ◽  
Vol 18 (5) ◽  
pp. 1634-1645 ◽  
Author(s):  
Loreana Gallo ◽  
Verónica Bucalá ◽  
María Verónica Ramírez-Rigo
Keyword(s):  
Sodium Cromoglycate ◽  
Pulmonary Delivery

scholarly journals Characterization of a Reverse-Phase Perfluorocarbon Emulsion for the Pulmonary Delivery of Tobramycin

2014 ◽  
Vol 27 (5) ◽  
pp. 392-399 ◽  
Author(s):  
Ryan A. Orizondo ◽  
Charlene Irvin Babcock ◽  
Mario L. Fabiilli ◽  
Leonid Pavlovsky ◽  
J. Brian Fowlkes ◽  
...  
Keyword(s):  
Pulmonary Delivery ◽  
Perfluorocarbon Emulsion ◽  
Reverse Phase

Development and Characterization of Spray Dried Microparticles for Pulmonary Delivery of Antifungal Drug

2015 ◽  
Vol 12 (4) ◽  
pp. 464-471 ◽  
Author(s):  
Divita Mathpal ◽  
Tarun Garg ◽  
Goutam Rath ◽  
Amit Goyal
Keyword(s):  
Pulmonary Delivery ◽  
Antifungal Drug ◽  
Spray Dried

Preparation and characterization of quercetin-loaded solid lipid microparticles for pulmonary delivery

2013 ◽  
Vol 239 ◽  
pp. 183-192 ◽  
Author(s):  
Luis Felipe Costa Silva ◽  
Georgia Kasten ◽  
Carlos Eduardo Maduro de Campos ◽  
Adilson Luiz Chinelatto ◽  
Elenara Lemos-Senna
Keyword(s):  
Pulmonary Delivery ◽  
Solid Lipid ◽  
Solid Lipid Microparticles ◽  
Lipid Microparticles
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