Large Scale Synthesis of Chiral (3Z,5Z)-2,7-Dihydro-1H-azepine-Derived Hamari Ligand for General Asymmetric Synthesis of Tailor-Made Amino Acids

2019 ◽  
Vol 23 (4) ◽  
pp. 619-628 ◽  
Author(s):  
Motohiro Takahashi ◽  
Hiroki Moriwaki ◽  
Toshio Miwa ◽  
Brittanie Hoang ◽  
Peng Wang ◽  
...  
Keyword(s):  
Amino Acids ◽  
Asymmetric Synthesis ◽  
Large Scale ◽  
Large Scale Synthesis

Exogenous Directing Group Free, Ligand-Enabled gamma-C(sp3)–H Arylation of Free Primary Aliphatic Amines and α-Amino Esters

2019 ◽  
Author(s):  
Yongzheng Ding ◽  
Shuai Fan ◽  
Xiaoxi Chen ◽  
yuzhen gao ◽  
Gang Li
Keyword(s):  
Amino Acids ◽  
Large Scale ◽  
Free Ligand ◽  
Aliphatic Amines ◽  
Rapid Synthesis ◽  
Amino Esters ◽  
Directing Group ◽  
Large Scale Synthesis ◽  
Primary Aliphatic Amines

A Pdᴵᴵ-catalyzed, ligand-enabled gamma-C(sp3)–H arylation of free primary aliphatic amines and amino esters without using an exogenous directing group is reported. This reaction is compatible with unhindered free aliphatic amines, and it is also be applicable to the rapid synthesis of biologically and synthetically valuable unnatural α-amino acids. Large scale synthesis is also feasible using this method.<br>

One-Pot, Large-Scale Synthesis of Nickel(II) Complexes Derived from 2-[N-(α-Picolyl)amino]benzophenone (PABP) and α- or β-Amino Acids

2007 ◽  
Vol 72 (23) ◽  
pp. 8932-8934 ◽  
Author(s):  
Guanghui Deng ◽  
Jiang Wang ◽  
Yu Zhou ◽  
Hualiang Jiang ◽  
Hong Liu
Keyword(s):  
Amino Acids ◽  
Large Scale ◽  
One Pot ◽  
Large Scale Synthesis

ChemInform Abstract: Convenient, Large-Scale Asymmetric Synthesis of β-Aryl-Substituted α,α-Difluoro-β-amino Acids.

ChemInform ◽  
2010 ◽  
Vol 33 (44) ◽  
pp. no-no
Author(s):  
Vadim A. Soloshonok ◽  
Hironari Ohkura ◽  
Alexander Sorochinsky ◽  
Natalia Voloshin ◽  
Andrey Markovsky ◽  
...  
Keyword(s):  
Amino Acids ◽  
Asymmetric Synthesis ◽  
Large Scale

Exogenous Directing Group Free, Ligand-Enabled gamma-C(sp3)–H Arylation of Free Primary Aliphatic Amines and α-Amino Esters

2019 ◽  
Author(s):  
Yongzheng Ding ◽  
Shuai Fan ◽  
Xiaoxi Chen ◽  
yuzhen gao ◽  
Gang Li
Keyword(s):  
Amino Acids ◽  
Large Scale ◽  
Free Ligand ◽  
Aliphatic Amines ◽  
Rapid Synthesis ◽  
Amino Esters ◽  
Directing Group ◽  
Large Scale Synthesis ◽  
Primary Aliphatic Amines

A Pdᴵᴵ-catalyzed, ligand-enabled gamma-C(sp3)–H arylation of free primary aliphatic amines and amino esters without using an exogenous directing group is reported. This reaction is compatible with unhindered free aliphatic amines, and it is also be applicable to the rapid synthesis of biologically and synthetically valuable unnatural α-amino acids. Large scale synthesis is also feasible using this method.<br>

ChemInform Abstract: The Large-Scale Synthesis of Unnatural Amino Acids

ChemInform ◽  
2010 ◽  
Vol 28 (40) ◽  
pp. no-no
Author(s):  
D. J. AGER ◽  
I. G. FOTHERINGHAM ◽  
S. A. LANEMAN ◽  
D. P. PANTALEONE ◽  
P. P. TAYLOR
Keyword(s):  
Amino Acids ◽  
Unnatural Amino Acids ◽  
Large Scale ◽  
Large Scale Synthesis

Convenient, large-scale asymmetric synthesis of β-aryl-substituted α,α-difluoro-β-amino acids

2002 ◽  
Vol 43 (31) ◽  
pp. 5445-5448 ◽  
Author(s):  
Vadim A Soloshonok ◽  
Hironari Ohkura ◽  
Alexander Sorochinsky ◽  
Natalia Voloshin ◽  
Andrey Markovsky ◽  
...  
Keyword(s):  
Amino Acids ◽  
Asymmetric Synthesis ◽  
Large Scale
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