Discovery of Investigational Drug CT1812, an Antagonist of the Sigma-2 Receptor Complex for Alzheimer’s Disease

2021 ◽  
Author(s):  
Gilbert M. Rishton ◽  
Gary C. Look ◽  
Zhi-Jie Ni ◽  
Jason Zhang ◽  
Yingcai Wang ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Investigational Drug ◽  
Receptor Complex

The N-methyl-d-aspartate receptor complex in Alzheimer's disease: reduced regulation by glycine but not zinc

1989 ◽  
Vol 500 (1-2) ◽  
pp. 369-373 ◽  
Author(s):  
Janet E. Steele ◽  
Alan M. Palmer ◽  
Gary C. Stratmann ◽  
David M. Bowen
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Receptor Complex ◽  
Aspartate Receptor

Loss of glycine-dependent radioligand binding to the receptor complex in patients with Alzheimer's disease

1989 ◽  
Vol 101 (1) ◽  
pp. 62-66 ◽  
Author(s):  
A.W. Procter ◽  
J.M. Stirling ◽  
G.C. Stratmann ◽  
A.J. Cross ◽  
D.M. Bowen
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Radioligand Binding ◽  
Receptor Complex
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