Lithium and Erectile Dysfunction: An Overview

Lithium has been a mainstay of therapy for patients with bipolar disorders for several decades. However, it may exert a variety of adverse effects that can affect patients’ compliance. Sexual and erectile dysfunction has been reported in several studies by patients who take lithium as monotherapy or combined with other psychotherapeutic agents. The exact mechanisms underlying such side effects of lithium are not completely understood. It seems that both central and peripheral mechanisms are involved in the lithium-related sexual dysfunction. Here, we had an overview of the epidemiology of lithium-related sexual and erectile dysfunction in previous clinical studies as well as possible pathologic pathways that could be involved in this adverse effect of lithium based on the previous preclinical studies. Understanding such mechanisms could potentially open a new avenue for therapies that can overcome lithium-related sexual dysfunction and improve patients’ adherence to the medication intake.

Assessment of Global COVID-19 on SMEs

The purpose of study is the assessment of global Covid-19 on small and medium scale enterprises (SMEs) with the case of Technological Incubation Centre (TIC), Ibadan. Three research objectives were raised. A descriptive survey research design was used. The population of the study is 29 (twenty-nine). Total Census survey was adopted as the sampling technique. SPSS software 20 analysis was used to analyze the data. The study concluded that, there has been increase in all the inputs needed for the production processes at the Centre. Therefore, sales of goods at the period of the Covid-19 have been negatively affected, which has similarly impacted on employment generation. It’s recommended that the management of the TIC should assist the businesses to mitigate the adverse effect of the Covid-19; while the Nigerian government should consider the SMEs as an important sub-sector that could restore the economy to the period of better economic growth.

Low level wind shear over Bomba airport

Significant climatological features based on 329 Low Level Wind Shear (LLWS) reports from 1985 to 1989 at Bombay airport are presented, The monsoon season has the highest frequency of occurrence of LLWS mainly due to thunderstorms and strong gusty winds, Other than monsoon season, occurrence of LLWS is related to sea and land breeze and nocturnal increase of surface temperature during night. The preferred time of occurrence of LLWS is between 0000 to 0600 IST and 1800 to 240J IST. The simultaneous occurrence of strong and severe LL WS, low cloud ceiling and very poor visibility has an adverse effect on aircraft operations at Bombay airport during landing and take-off.

Medicinal Plants

Medicines of plant origin have been used for treating humans and animals without any adverse effects. New medicinal plants are searched to develop more effective and cheaper drugs in place of synthetics drugs. Plants represent a large natural source of compounds that might serve for the development of novel drugs. Currently medicinal herbs are researched for diuretic properties, and several medicinal herbs are used as diuretics. Currently various synthetic medicines are available for this purpose; however, natural resource medicines are still an important choice because of their higher efficiency and better safety. Further, some herbs are also important sources of antioxidants, which protect the body from the effects of free radicals produced in the body. Antioxidants are required by our body due to increase in the likely exposure of the body to harmful pollutants, radiation, UV lights, etc. These have the ability to delay the oxidation, and plant-derived products are of great interest due to the adverse effect of antibiotics.