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The review is an attempt to introduce the readers in brief about biofilms and their implications as well as some
new perceptions in biotechnology. Biofilms are adherent microbial communities, which are developed on submerged
surfaces in aquatic environments. Biofilms play a significant role in exopolymer production, material deterioration and also
cause harmful infections. Further, the role of corrosion causing biofilm bacteria in deterioration of different materials,
microbial biofilms and their enzymatic processes in reducing the toxicity of pollutants in industrial effluents are elaborated,
along with clean technologies for wastewater treatment. Biotechnology is defined as any technological application that uses
biological systems to synthesize or modify products or processes. The applications include biochemical processes, medical
care, cell and tissue culture as well as synthetic biology and others. Synthetic biology details about the design, construction
of new biological components and systems for useful purposes. Finally, to overcome the limitations that are inherent to the
use of cellular host’s, cell-free systems as critical platforms for synthetic biology applications. This mini-review also
mentions about new diagnostic products based on enzymes, monoclonal antibodies and engineered proteins as well as novel
prophylactic vaccines.