Covalent thrombin-.alpha.2-macroglobulin complexes. Evidence for bivalent crosslinking of inhibitor chains by a single enzyme molecule

Biochemistry ◽  
1984 ◽  
Vol 23 (12) ◽  
pp. 2807-2811 ◽  
Author(s):  
Dalton Wang ◽  
Anna I. Yuan ◽  
Richard D. Feinman

2016 ◽  
Vol 27 (15) ◽  
pp. 155502 ◽  
Author(s):  
ShengWei Tan ◽  
DeJian Gu ◽  
Hang Liu ◽  
QuanJun Liu


2004 ◽  
Vol 3 (3) ◽  
pp. 87
Author(s):  
Vida Foubister


2003 ◽  
Vol 25 (4) ◽  
pp. 24-27 ◽  
Author(s):  
Clive R. Bagshaw

In the last decade, several methods have been developed to measure enzyme activity at the level of a single enzyme molecule. This represents a considerable technical feat, but what does it allow us to learn about enzymes? Here, the basic principles are reviewed to show that new forms of heterogeneity in activity may be revealed and evidence gained for rare states that would otherwise be swamped in bulk assays.



2020 ◽  
Vol 32 (1) ◽  
pp. 301-306
Author(s):  
Nan Cheng ◽  
Zhuo Zhen Chen ◽  
Angelique Florentinus-Mefailoski ◽  
Ming Miao ◽  
John G Marshall


2003 ◽  
pp. 293-301 ◽  
Author(s):  
Robert Polakowski ◽  
Michael Eggertson ◽  
Douglas B. Craig ◽  
Norman J. Dovichi


1998 ◽  
Vol 70 (1) ◽  
pp. 39A-43A ◽  
Author(s):  
Douglas B. Craig ◽  
Edgar Arriaga ◽  
Jerome C. Y. Wong ◽  
Hui Lu ◽  
and Norman J. Dovichi


2017 ◽  
Vol 27 ◽  
pp. 238-239
Author(s):  
Alina N. Sekretaryova ◽  
Mikhail Yu. Vagin ◽  
Anthony P.F. Turner ◽  
Mats Eriksson


ACS Nano ◽  
2008 ◽  
Vol 2 (12) ◽  
pp. 2437-2440 ◽  
Author(s):  
Allen J. Bard


ACS Nano ◽  
2008 ◽  
Vol 2 (12) ◽  
pp. 2497-2504 ◽  
Author(s):  
Freek J. M. Hoeben ◽  
F. Stefan Meijer ◽  
Cees Dekker ◽  
Simon P. J. Albracht ◽  
Hendrik A. Heering ◽  
...  


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