Novel Antimalarial Agent Found

2015 ◽  
Vol 93 (25) ◽  
pp. 6 ◽  
Keyword(s):  
Antimalarial Agent

Newbouldiaquinone A: A naphthoquinone–anthraquinone ether coupled pigment, as a potential antimicrobial and antimalarial agent from Newbouldia laevis

2006 ◽  
Vol 67 (6) ◽  
pp. 605-609 ◽  
Author(s):  
Kenneth Oben Eyong ◽  
Gabriel Ngosong Folefoc ◽  
Victor Kuete ◽  
Veronique Penlap Beng ◽  
Karsten Krohn ◽  
...  
Keyword(s):  
Antimalarial Agent

scholarly journals Methnaridine is an orally bioavailable, fast‐killing and long‐acting antimalarial agent that cures Plasmodium infections in mice

2020 ◽  
Vol 177 (24) ◽  
pp. 5569-5579
Author(s):  
Weisi Wang ◽  
Junmin Yao ◽  
Zhuo Chen ◽  
Yiming Sun ◽  
Yuqing Shi ◽  
...  
Keyword(s):  
Antimalarial Agent ◽  
Orally Bioavailable ◽  
Long Acting

Structure−Activity Relationships of the Antimalarial Agent Artemisinin. 4. Effect of Substitution at C-3

1996 ◽  
Vol 39 (15) ◽  
pp. 2900-2906 ◽  
Author(s):  
Mitchell A. Avery ◽  
Sanjiv Mehrotra ◽  
Jason D. Bonk ◽  
Jeffrey A. Vroman ◽  
D. Keith Goins ◽  
...  
Keyword(s):  
Antimalarial Agent ◽  
Structure Activity Relationships ◽  
Structure Activity

Enantioselective LC/MS method for the determination of an antimalarial agent Fenozan B07 in dog plasma

Chirality ◽  
2006 ◽  
Vol 18 (5) ◽  
pp. 297-305 ◽  
Author(s):  
Ciriaco Maraschiello ◽  
Jaume Vilageliu ◽  
Isabel Dorronsoro ◽  
Ana Martinez ◽  
Pablo Floriano ◽  
...  
Keyword(s):  
Antimalarial Agent ◽  
Dog Plasma

Synthesis and molecular docking studies of chalcones derivatives as potential antimalarial agent

2021 ◽  
Author(s):  
Nurlaili ◽  
Helvina Saputri ◽  
Sri Zulfiza Nasution ◽  
Rahmiwati Hilma ◽  
Jufrizal Syahri
Keyword(s):  
Molecular Docking ◽  
Docking Studies ◽  
Antimalarial Agent ◽  
Molecular Docking Studies

scholarly journals Repositioning Salirasib as New Antimalarial Agent

2018 ◽  
Author(s):  
Exequiel O. J. Porta ◽  
Ignasi Bofill Verdaguer ◽  
Consuelo Perez ◽  
Claudia Banchio ◽  
Mauro Ferreira de Azevedo ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Antimalarial Drugs ◽  
Antiplasmodial Activity ◽  
Eukaryotic Cells ◽  
Activity Relationship ◽  
Activity Assay ◽  
Antimalarial Agent ◽  
Micromolar Concentration ◽  
Structure Activity ◽  
Low Cytotoxicity

<p>The antiplasmodial activity assay was performed using a simple, high-sensitivity methodology based on nanoluciferase (nLuc)-transfected <i>P. falciparum </i>parasites. The results showed that some of the analogs were active at low micromolar concentration. The most potent member of the series has S-farnesyl and the triazole moiety substituted with methyl-naphtyl. The low cytotoxicity in eukaryotic cells of the most active analogs provided good therapeutic indexes, being promising candidates for future antimalarial drugs development. Our results provide structure-activity relationship data for the design of new antimalarial drugs. </p>

Synthesis of an 8-pentafluorosulfanyl analog of the antimalarial agent mefloquine

2010 ◽  
Vol 51 (39) ◽  
pp. 5137-5140 ◽  
Author(s):  
Tingting Mo ◽  
Xueling Mi ◽  
Erin E. Milner ◽  
Geoffrey S. Dow ◽  
Peter Wipf
Keyword(s):  
Antimalarial Agent

scholarly journals Assay method for quality control and stability studies of a new antimalarial agent (CDRI 99/411)

2013 ◽  
Vol 3 (5) ◽  
pp. 335-340 ◽  
Author(s):  
Kiran Khandelwal ◽  
Shakti Deep Pachauri ◽  
Sofia Zaidi ◽  
Pankaj Dwivedi ◽  
Ashok Kumar Sharma ◽  
...  
Keyword(s):  
Quality Control ◽  
Assay Method ◽  
Stability Studies ◽  
Antimalarial Agent

A Novel Short and Efficient Synthetic Route to the Antimalarial Agent FR900098 and Derivatives

Synthesis ◽  
2007 ◽  
Vol 2007 (22) ◽  
pp. 3553-3557 ◽  
Author(s):  
Martin Schlitzer ◽  
Johann Perruchon ◽  
Regina Ortmann
Keyword(s):  
Synthetic Route ◽  
Antimalarial Agent

Conformational analysis of the antimalarial agent quinidine

1997 ◽  
Vol 5 (2) ◽  
pp. 353-361 ◽  
Author(s):  
Thais H.A. Silva ◽  
Alaíde B. Oliveira ◽  
Wagner B. De Almeida
Keyword(s):  
Conformational Analysis ◽  
Antimalarial Agent
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