A new method for the synthesis of cyclopentenones via the tandem Michael addition-carbene insertion reaction of .beta.-ketoethynyl(phenyl)iodonium salts

1994 ◽  
Vol 116 (1) ◽  
pp. 93-98 ◽  
Author(s):  
Bobby L. Williamson ◽  
Rik R. Tykwinski ◽  
Peter J. Stang
Keyword(s):  
Michael Addition ◽  
New Method ◽  
Insertion Reaction ◽  
Iodonium Salts ◽  
Carbene Insertion

scholarly journals Organocatalytic Asymmetric Synthesis of α-Amino Esters from Sulfoxonium Ylides

2021 ◽  
Author(s):  
Wengang Guo ◽  
Hai Huang ◽  
Jianwei Sun
Keyword(s):  
Asymmetric Synthesis ◽  
Insertion Reaction ◽  
Metal Catalyst ◽  
Insertion Reactions ◽  
Amino Esters ◽  
Carbene Insertion

Described here is the first organocatalytic asymmetric N−H insertion reaction of α-carbonyl sulfoxonium ylides. Without a metal catalyst, this reaction represents an attractive complement to the well-established carbene insertion reactions....

A stereocontrolled, enantiomerically specific total synthesis of thienamycin

1980 ◽  
Vol 289 (1036) ◽  
pp. 191-195 ◽  
Keyword(s):  
Total Synthesis ◽  
Aspartic Acid ◽  
Ring System ◽  
Insertion Reaction ◽  
Carbene Insertion ◽  
Metal Catalyzed

A versatile stereocontrolled total synthesis of thienamycin starting from L-aspartic acid is reported. Stereocontrol is achieved by potassium tri- sec -butylborohydride reduction of a thermodynamically formed 3α-acetylazetidinone intermediate. The key [3.2.0] bicyclic ring system is prepared by a metal catalyzed carbene insertion reaction.

scholarly journals A NOVEL, CYCLOBUTANONE-FORMING CARBENE INSERTION REACTION. TETRACYCLO[7.3.1.02,5.05,10]TRIDECAN-4-ONE FROM 1-(TRICYCLO[5.3.1.03,8]UNDEC-3-YL)-2-DIAZOETHAN-1-ONE

1975 ◽  
Vol 4 (9) ◽  
pp. 957-960 ◽  
Author(s):  
Naotake Takaishi ◽  
Yoshiaki Fujikura ◽  
Yoshiaki Inamoto ◽  
Hiroshi Ikeda
Keyword(s):  
Insertion Reaction ◽  
Carbene Insertion
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