scholarly journals Spin-Center Shift-Enabled Direct Enantioselective α-Benzylation of Aldehydes with Alcohols

2018 ◽  
Vol 140 (9) ◽  
pp. 3322-3330 ◽  
Author(s):  
Eric D. Nacsa ◽  
David W. C. MacMillan
Keyword(s):  
Center Shift ◽  
Spin Center

ChemInform Abstract: Spin-Center Shift Reactions

ChemInform ◽  
2012 ◽  
Vol 43 (38) ◽  
pp. no-no
Author(s):  
Pablo Wessig
Keyword(s):  
Center Shift ◽  
Spin Center

scholarly journals Ketones and aldehydes as alkyl radical equivalents for C─H functionalization of heteroarenes

2019 ◽  
Vol 5 (10) ◽  
pp. eaax9955 ◽  
Author(s):  
Jianyang Dong ◽  
Zhen Wang ◽  
Xiaochen Wang ◽  
Hongjian Song ◽  
Yuxiu Liu ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Carbon Atom ◽  
Alkyl Radical ◽  
Carbonyl Carbon ◽  
Center Shift ◽  
Catalytic Activation ◽  
Proton Coupled Electron Transfer ◽  
Spin Center ◽  
Direct Attack

The polar nature of the C═O bond commonly allows it to undergo direct attack by nucleophiles at the electrophilic carbon atom in which ketones and aldehydes act as alkyl carbocation equivalents. In contrast, transformations in which ketones and aldehydes act as alkyl radical equivalents (generated in carbonyl carbon) are unknown. Here, we describe a new catalytic activation mode that combines proton-coupled electron transfer (PCET) with spin-center shift (SCS) and enables C─H alkylation of heteroarenes using ketones and aldehydes as alkyl radical equivalents. This transformation proceeded via reductive PCET activation of the ketones and aldehydes to form α-oxy radicals, addition of the radicals to the N-heteroarenes to form C─C bonds, and SCS to cleave the C─O bonds of the resulting alcohols. This mild protocol represents a general use of abundant, commercially available, ketones and aldehydes as latent alkyl radical equivalents.

scholarly journals Excited-State Palladium-Catalyzed 1,2-Spin-Center Shift Enables Selective C-2 Reduction, Deuteration, and Iodination of Carbohydrates

2021 ◽  
Vol 143 (4) ◽  
pp. 1728-1734
Author(s):  
Gaoyuan Zhao ◽  
Wang Yao ◽  
Jaclyn N. Mauro ◽  
Ming-Yu Ngai
Keyword(s):  
Excited State ◽  
Center Shift ◽  
Spin Center ◽  
Palladium Catalyzed

Spin-Center Shift (SCS) — A Versatile Concept in Biological and Synthetic Chemistry

ChemInform ◽  
2007 ◽  
Vol 38 (32) ◽  
Author(s):  
Pablo Wessig ◽  
Olaf Muehling
Keyword(s):  
Synthetic Chemistry ◽  
Center Shift ◽  
Spin Center

Spin-Center Shift (SCS) – A Versatile Concept in Biological and Synthetic Chemistry

2007 ◽  
Vol 2007 (14) ◽  
pp. 2219-2232 ◽  
Author(s):  
Pablo Wessig ◽  
Olaf Muehling
Keyword(s):  
Synthetic Chemistry ◽  
Center Shift ◽  
Spin Center

Numerical computation and characteristic analysis on the center shift of fire whirls in a ship engine room fire

2012 ◽  
Vol 50 (1) ◽  
pp. 12-18 ◽  
Author(s):  
Su Shichuan ◽  
Wang Liang ◽  
Nie Yuhong ◽  
Gu Xiang
Keyword(s):  
Numerical Computation ◽  
Characteristic Analysis ◽  
Center Shift ◽  
Engine Room

Dynamic Measurement of Refraction and Pupil Center Shift according to Illumination

2021 ◽  
Vol 23 (1) ◽  
pp. 33-39
Author(s):  
Hyun-Jong Cho ◽  
◽  
Hyojin Kim
Keyword(s):  
Dynamic Measurement ◽  
Center Shift ◽  
Pupil Center
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