Luteinizing hormone releasing hormone. Solid-phase synthesis of a 5-phenylalanine analog possessing high biological activity

1973 ◽  
Vol 16 (1) ◽  
pp. 83-84 ◽  
Author(s):  
David H. Coy ◽  
Esther J. Coy ◽  
Andrew V. Schally
Keyword(s):  
Biological Activity ◽  
Luteinizing Hormone ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
High Biological Activity ◽  
Phase Synthesis ◽  
Luteinizing Hormone Releasing Hormone ◽  
Releasing Hormone

Solid phase synthesis and biological activities of oxytocin carba analogues containing threonine in position 4

1985 ◽  
Vol 50 (2) ◽  
pp. 418-427 ◽  
Author(s):  
Michal Lebl ◽  
Victor J. Hruby ◽  
Jiřina Slaninová ◽  
Tomislav Barth
Keyword(s):  
Biological Activity ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Biological Activities ◽  
High Biological Activity ◽  
Phase Synthesis

Solis phase methodology was developed for the synthesis of carba-analogues of oxytocin. Two known compounds (deamino-1-carba-oxytocin (I) and deamino-6-carba-oxytocin (II)) and two new analogues ([4-threonine]deamino-1-carba-oxytocin (III) and [4-threonine]deamino-6-carba-oxytocin (IV)) were synthesized using different approaches. The latter two compounds were found to possess high biological activity in the rat uterotonic (in vitro and in vivo) and galactogogic (in vivo) assays.

New Gly-Pro-Glu (GPE) analogues: Expedite solid-phase synthesis and biological activity

2006 ◽  
Vol 16 (5) ◽  
pp. 1392-1396 ◽  
Author(s):  
Sergio A. Alonso De Diego ◽  
Marta Gutiérrez-Rodríguez ◽  
M. Jesús Pérez de Vega ◽  
Diego Casabona ◽  
Carlos Cativiela ◽  
...  
Keyword(s):  
Biological Activity ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis

ChemInform Abstract: SYNTHESIS AND BIOLOGICAL ACTIVITY OF PEPTIDE ANTAGONISTS OF LULIBERIN (LUTEINIZING HORMONE-RELEASING HORMONE)

1980 ◽  
Vol 11 (16) ◽  
Author(s):  
G. W. MOERSCH ◽  
M. C. REBSTOCK ◽  
E. L. WITTLE ◽  
F. J. TINNEY ◽  
E. D. NICOLAIDES ◽  
...  
Keyword(s):  
Biological Activity ◽  
Luteinizing Hormone ◽  
Luteinizing Hormone Releasing Hormone ◽  
Releasing Hormone

Solid-phase synthesis and in vitro biological activity of a Thr4→Ser4 analog of daptomycin

2015 ◽  
Vol 25 (23) ◽  
pp. 5490-5494 ◽  
Author(s):  
Chuda Raj Lohani ◽  
Robert Taylor ◽  
Michael Palmer ◽  
Scott D. Taylor
Keyword(s):  
Biological Activity ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis
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