3-Phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and Analogues:  High-Affinity γ-Aminobutyric Acid-A Benzodiazepine Receptor Ligands with α2, α3, and α5-Subtype Binding Selectivity over α1

Specific high-affinity binding of peripheral benzodiazepine receptor ligands to brain tumors in rat and man

Cancer ◽

10.1002/1097-0142(19900101)65:1<93::aid-cncr2820650120>3.0.co;2-1 ◽

1990 ◽

Vol 65 (1) ◽

pp. 93-97 ◽

Cited By ~ 45

Author(s):

Keith L. Black ◽

Kiyonobu Ikezaki ◽

Emily Santori ◽

Donald P. Becker ◽

Harry V. Vinters

Keyword(s):

Brain Tumors ◽

Benzodiazepine Receptor ◽

Affinity Binding ◽

Peripheral Benzodiazepine Receptor ◽

Receptor Ligands ◽

High Affinity Binding ◽

Benzodiazepine receptor ligands. 8: Synthesis and pharmacological evaluation of new pyrazolo[5,1-c] [1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: High affinity ligands endowed with inverse-agonist pharmacological efficacy

10.1016/j.bmc.2005.08.058 ◽

2006 ◽

Vol 14 (3) ◽

pp. 758-775 ◽

Cited By ~ 24

Author(s):

Gabriella Guerrini ◽

Annarella Costanzo ◽

Giovanna Ciciani ◽

Fabrizio Bruni ◽

Silvia Selleri ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Inverse Agonist ◽

Receptor Ligands ◽

Affinity Ligands ◽

High Affinity ◽

Pharmacological Evaluation

High affinity central benzodiazepine receptor ligands. Part 2: quantitative structure–activity relationships and comparative molecular field analysis of pyrazolo[4,3- c ]quinolin-3-ones

10.1016/s0968-0896(00)00262-5 ◽

2001 ◽

Vol 9 (2) ◽

pp. 431-444 ◽

Cited By ~ 18

Author(s):

L. Savini ◽

L. Chiasserini ◽

C. Pellerano ◽

G. Biggio ◽

E. Maciocco ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Field Analysis ◽

Comparative Molecular Field Analysis ◽

Quantitative Structure ◽

Receptor Ligands ◽

Quantitative Structure Activity Relationships

High Affinity ◽

Structure Activity ◽

Central Benzodiazepine Receptor ◽

Inhibition of γ-aminobutyric acid stimulated [3H]diazepam binding by benzodiazepine receptor ligands

Biochemical Pharmacology ◽

10.1016/0006-2952(81)90240-9 ◽

1981 ◽

Vol 30 (15) ◽

pp. 2171-2174 ◽

Cited By ~ 21

Author(s):

Paul J. Marangos ◽

Steven M. Paul ◽

Alexandra M. Parma ◽

Philip Skolnick

Keyword(s):

Benzodiazepine Receptor ◽

Aminobutyric Acid ◽

Receptor Ligands ◽

Benzodiazepine Receptor Ligands

High-affinity benzodiazepine receptor ligands among benzodiazepines and betacarbolines with different intrinsic activity

International Journal of Quantum Chemistry ◽

10.1002/qua.560360721 ◽

2009 ◽

Vol 36 (S16) ◽

pp. 273-280

Author(s):

A. Yliniemelä ◽

J. Gynther ◽

H. Konschin ◽

H. Tylli ◽

J. Rouvinen

Keyword(s):

Benzodiazepine Receptor ◽

Intrinsic Activity ◽

Receptor Ligands ◽

High affinity central benzodiazepine receptor ligands. Part 3: insights into the pharmacophore and pattern recognition study of intrinsic activities of pyrazolo[4,3- c ]quinolin-3-ones

10.1016/s0968-0896(03)00527-3 ◽

2003 ◽

Vol 11 (23) ◽

pp. 5259-5272 ◽

Cited By ~ 18

Author(s):

Andrea Carotti ◽

Cosimo Altomare ◽

Luisa Savini ◽

Luisa Chiasserini ◽

Cesare Pellerano ◽

...

Keyword(s):

Pattern Recognition ◽

Benzodiazepine Receptor ◽

Receptor Ligands ◽

High Affinity ◽

Central Benzodiazepine Receptor

γ-Aminobutyric acid modulation of benzodiazepine receptor binding in vitro does not predict the pharmacologic activity of all benzodiazepine receptor ligands

Neuroscience Letters ◽

10.1016/s0304-3940(85)80074-4 ◽

1985 ◽

Vol 54 (2-3) ◽

pp. 173-177 ◽

Cited By ~ 10

Author(s):

A.Y. Chweh ◽

E.A. Swinyard ◽

H.H. Wolf

Keyword(s):

Receptor Binding ◽

Benzodiazepine Receptor ◽

Aminobutyric Acid ◽

Receptor Ligands ◽

Pharmacologic Activity

A comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2007.04690.x ◽

2007 ◽

Vol 102 (6) ◽

pp. 2118-2131 ◽

Cited By ~ 39

Author(s):

Sriram Venneti ◽

Brian J. Lopresti ◽

Guoji Wang ◽

Susan L. Slagel ◽

N. Scott Mason ◽

...

Keyword(s):

Pet Imaging ◽

Microglial Activation ◽

Benzodiazepine Receptor ◽

Peripheral Benzodiazepine Receptor ◽

Receptor Ligands ◽

Rat Models ◽

High Affinity Central Benzodiazepine Receptor Ligands: Synthesis and Biological Evaluation of a Series of Phenyltriazolobenzotriazindione Derivatives

Journal of Medicinal Chemistry ◽

10.1021/jm0408722 ◽

2005 ◽

Vol 48 (8) ◽

pp. 2936-2943 ◽

Cited By ~ 5

Author(s):

Giampaolo Primofiore ◽

Federico Da Settimo ◽

Sabrina Taliani ◽

Silvia Salerno ◽

Ettore Novellino ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Biological Evaluation ◽

Receptor Ligands ◽

Synthesis And Biological Evaluation

High Affinity ◽

Central Benzodiazepine Receptor ◽

High affinity central benzodiazepine receptor ligands: synthesis and structure–activity relationship studies of a new series of pyrazolo[4,3- c ]quinolin-3-ones

10.1016/s0968-0896(97)10039-6 ◽

1998 ◽

Vol 6 (4) ◽

pp. 389-399 ◽

Cited By ~ 28

Author(s):

L. Savini ◽

P. Massarelli ◽

C. Nencini ◽

C. Pellerano ◽

G. Biggio ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Receptor Ligands ◽

High Affinity ◽

Structure Activity ◽

Central Benzodiazepine Receptor