Synthesis, in Vitro Pharmacology, Structure−Activity Relationships, and Pharmacokinetics of 3-Alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Derivatives as Potent and Selective Group II Metabotropic Glutamate Receptor Antagonists

2004 ◽  
Vol 47 (18) ◽  
pp. 4570-4587 ◽  
Author(s):  
Atsuro Nakazato ◽  
Kazunari Sakagami ◽  
Akito Yasuhara ◽  
Hiroshi Ohta ◽  
Ryoko Yoshikawa ◽  
...  
Keyword(s):  
Dicarboxylic Acid ◽  
Glutamate Receptor ◽  
Metabotropic Glutamate Receptor ◽  
Receptor Antagonists ◽  
Structure Activity Relationships ◽  
Metabotropic Glutamate ◽  
Structure Activity ◽  
Glutamate Receptor Antagonists ◽  
In Vitro Pharmacology

Predicting Compound Selectivity by Self-Organizing Maps: Cross-Activities of Metabotropic Glutamate Receptor Antagonists

ChemMedChem ◽  
2006 ◽  
Vol 1 (10) ◽  
pp. 1066-1068 ◽  
Author(s):  
Tobias Noeske ◽  
Britta C. Sasse ◽  
Holger Stark ◽  
Christopher G. Parsons ◽  
Tanja Weil ◽  
...  
Keyword(s):  
Glutamate Receptor ◽  
Metabotropic Glutamate Receptor ◽  
Receptor Antagonists ◽  
Self Organizing Maps ◽  
Metabotropic Glutamate ◽  
Glutamate Receptor Antagonists ◽  
Self Organizing
Sign in / Sign up

Export Citation Format

Share Document