Design of 2,5-Dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and Structure−Activity Relationships of a Series of Potent and Orally Active Corticotropin-Releasing Factor Receptor Antagonists

2004 ◽  
Vol 47 (19) ◽  
pp. 4787-4798 ◽  
Author(s):  
Chen ◽  
Keith M. Wilcoxen ◽  
Charles Q. Huang ◽  
Yun-Feng Xie ◽  
James R. McCarthy ◽  
...  
Keyword(s):  
Corticotropin Releasing Factor ◽  
Receptor Antagonists ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Orally Active

Dihydropyridopyrazinones and Dihydropteridinones as Corticotropin-Releasing Factor-1 Receptor Antagonists:  Structure−Activity Relationships and Computational Modeling

2007 ◽  
Vol 50 (9) ◽  
pp. 2269-2272 ◽  
Author(s):  
Carolyn D. Dzierba ◽  
Andrew J. Tebben ◽  
Richard G. Wilde ◽  
Amy G. Takvorian ◽  
Maria Rafalski ◽  
...  
Keyword(s):  
Computational Modeling ◽  
Corticotropin Releasing Factor ◽  
Receptor Antagonists ◽  
Structure Activity Relationships ◽  
Structure Activity

Synthesis and structure–activity relationships of N3-pyridylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists

2010 ◽  
Vol 20 (6) ◽  
pp. 1890-1894 ◽  
Author(s):  
Richard A. Hartz ◽  
Vijay T. Ahuja ◽  
William D. Schmitz ◽  
Thaddeus F. Molski ◽  
Gail K. Mattson ◽  
...  
Keyword(s):  
Corticotropin Releasing Factor ◽  
Receptor Antagonists ◽  
Structure Activity Relationships ◽  
Crf1 Receptor ◽  
Structure Activity

Rational Design, Synthesis, and Structure−Activity Relationships of Aryltriazoles as Novel Corticotropin-Releasing Factor-1 Receptor Antagonists

2005 ◽  
Vol 48 (5) ◽  
pp. 1540-1549 ◽  
Author(s):  
Richard F. Lowe ◽  
Jodene Nelson ◽  
Trunghau N. Dang ◽  
Paul D. Crowe ◽  
Anil Pahuja ◽  
...  
Keyword(s):  
Rational Design ◽  
Corticotropin Releasing Factor ◽  
Receptor Antagonists ◽  
Design Synthesis ◽  
Structure Activity Relationships ◽  
Structure Activity
Sign in / Sign up

Export Citation Format

Share Document