Synthesis and Biological Evaluation of Substituted [18F]Imidazo[1,2-a]pyridines and [18F]Pyrazolo[1,5-a]pyrimidines for the Study of the Peripheral Benzodiazepine Receptor Using Positron Emission Tomography

Christopher J. R. Fookes; Tien Q. Pham; Filomena Mattner; Ivan Greguric; Christian Loc’h; Xiang Liu; Paula Berghofer; Rachael Shepherd; Marie-Claude Gregoire; Andrew Katsifis

doi:10.1021/jm7014556

Synthesis and Biological Evaluation of Substituted [18F]Imidazo[1,2-a]pyridines and [18F]Pyrazolo[1,5-a]pyrimidines for the Study of the Peripheral Benzodiazepine Receptor Using Positron Emission Tomography

Journal of Medicinal Chemistry ◽

10.1021/jm7014556 ◽

2008 ◽

Vol 51 (13) ◽

pp. 3700-3712 ◽

Cited By ~ 90

Author(s):

Christopher J. R. Fookes ◽

Tien Q. Pham ◽

Filomena Mattner ◽

Ivan Greguric ◽

Christian Loc’h ◽

...

Keyword(s):

Positron Emission Tomography ◽

Benzodiazepine Receptor ◽

Biological Evaluation ◽

Emission Tomography ◽

Peripheral Benzodiazepine Receptor ◽

Positron Emission ◽

Synthesis And Biological Evaluation

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[2-11C]Isopropyl-, [1-11C]Ethyl-, and [11C]Methyl-Labeled Phenoxyphenyl Acetamide Derivatives as Positron Emission Tomography Ligands for the Peripheral Benzodiazepine Receptor: Radiosynthesis, Uptake, and in Vivo Binding in Brain

Journal of Medicinal Chemistry ◽

10.1021/jm060006k ◽

2006 ◽

Vol 49 (9) ◽

pp. 2735-2742 ◽

Cited By ~ 21

Author(s):

Ming-Rong Zhang ◽

Masanao Ogawa ◽

Jun Maeda ◽

Takehito Ito ◽

Junko Noguchi ◽

...

Keyword(s):

Positron Emission Tomography ◽

Benzodiazepine Receptor ◽

Emission Tomography ◽

Peripheral Benzodiazepine Receptor ◽

In Vivo Binding ◽

Positron Emission

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Whole-body distribution and metabolism of [N-methyl-11C](R)-1-(2-chlorophenyl)-N-(1-methylpropyl)-3-isoquinolinecarboxamide in humans; an imaging agent for in vivo assessment of peripheral benzodiazepine receptor activity with positron emission tomography

European Journal of Nuclear Medicine and Molecular Imaging ◽

10.1007/s00259-008-1000-1 ◽

2008 ◽

Vol 36 (4) ◽

pp. 671-682 ◽

Cited By ~ 23

Author(s):

Anne Roivainen ◽

Kjell Någren ◽

Jussi Hirvonen ◽

Vesa Oikonen ◽

Pauliina Virsu ◽

...

Keyword(s):

Positron Emission Tomography ◽

Benzodiazepine Receptor ◽

Receptor Activity ◽

Emission Tomography ◽

Whole Body ◽

Peripheral Benzodiazepine Receptor ◽

Body Distribution ◽

Positron Emission ◽

In Vivo Assessment

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Positron emission tomography imaging of peripheral benzodiazepine receptor binding in human immunodeficiency virus–infected subjects with and without cognitive impairment

Journal of NeuroVirology ◽

10.1080/13550280600873868 ◽

2006 ◽

Vol 12 (4) ◽

pp. 262-271 ◽

Cited By ~ 38

Author(s):

Clayton Wiley ◽

Brian Lopresti ◽

James Becker ◽

Fernando Boada ◽

Oscar Lopez ◽

...

Keyword(s):

Positron Emission Tomography ◽

Human Immunodeficiency Virus ◽

Cognitive Impairment ◽

Positron Emission Tomography Imaging ◽

Benzodiazepine Receptor ◽

Emission Tomography ◽

Peripheral Benzodiazepine Receptor ◽

Tomography Imaging ◽

Positron Emission ◽

Immunodeficiency Virus

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Synthesis and biological evaluation of potential positron emission tomography (PET) ligands for brain visualization of dopamine D3 receptors

ARKIVOC ◽

10.3998/ark.5550190.0007.811 ◽

2006 ◽

Vol 2006 (8) ◽

pp. 102-110 ◽

Cited By ~ 1

Author(s):

Enza Lacivita ◽

Francesco Berardi ◽

Nicola A. Colabufo ◽

Marcello Leopoldo ◽

Roberto Perrone ◽

...

Keyword(s):

Positron Emission Tomography ◽

Biological Evaluation ◽

Emission Tomography ◽

Dopamine D3 Receptors ◽

D3 Receptors ◽

Positron Emission ◽

Dopamine D3 ◽

Synthesis And Biological Evaluation

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Synthesis and Biological Evaluation of the Mitochondrial Complex 1 Inhibitor 2-[4-(4-Fluorobutyl)benzylsulfanyl]-3-methylchromene-4-one as a Potential Cardiac Positron Emission Tomography Tracer

Journal of Medicinal Chemistry ◽

10.1021/jm0701831 ◽

2007 ◽

Vol 50 (18) ◽

pp. 4304-4315 ◽

Cited By ~ 8

Author(s):

Heike Radeke ◽

Kelley Hanson ◽

Padmaja Yalamanchili ◽

Megan Hayes ◽

Zhi-Qin Zhang ◽

...

Keyword(s):

Positron Emission Tomography ◽

Biological Evaluation ◽

Emission Tomography ◽

Positron Emission Tomography Tracer ◽

Mitochondrial Complex ◽

Cardiac Positron Emission Tomography ◽

Positron Emission ◽

Synthesis And Biological Evaluation

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Synthesis and Biological Evaluation of Pyridazinone Analogues as Potential Cardiac Positron Emission Tomography Tracers

Journal of Medicinal Chemistry ◽

10.1021/jm701443n ◽

2008 ◽

Vol 51 (10) ◽

pp. 2954-2970 ◽

Cited By ~ 21

Author(s):

Ajay Purohit ◽

Heike Radeke ◽

Michael Azure ◽

Kelley Hanson ◽

Richard Benetti ◽

...

Keyword(s):

Positron Emission Tomography ◽

Biological Evaluation ◽

Emission Tomography ◽

Cardiac Positron Emission Tomography ◽

Positron Emission ◽

Synthesis And Biological Evaluation

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Synthesis and biological evaluation of 68Ga-bis-DOTA-PA as a potential agent for positron emission tomography imaging of necrosis

Nuclear Medicine and Biology ◽

10.1016/j.nucmedbio.2013.04.011 ◽

2013 ◽

Vol 40 (6) ◽

pp. 816-822 ◽

Cited By ~ 7

Author(s):

Kristof Prinsen ◽

Marlein M. Cona ◽

Bernard J. Cleynhens ◽

Junjie Li ◽

Hubert Vanbilloen ◽

...

Keyword(s):

Positron Emission Tomography ◽

Positron Emission Tomography Imaging ◽

Biological Evaluation ◽

Emission Tomography ◽

Tomography Imaging ◽

Positron Emission ◽

Synthesis And Biological Evaluation

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Increased binding of peripheral benzodiazepine receptor in mild cognitive impairment–dementia converters measured by positron emission tomography with [11C]DAA1106

Psychiatry Research Neuroimaging ◽

10.1016/j.pscychresns.2011.08.013 ◽

2012 ◽

Vol 203 (1) ◽

pp. 67-74 ◽

Cited By ~ 86

Author(s):

Fumihiko Yasuno ◽

Jun Kosaka ◽

Miho Ota ◽

Makoto Higuchi ◽

Hiroshi Ito ◽

...

Keyword(s):

Positron Emission Tomography ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Benzodiazepine Receptor ◽

Emission Tomography ◽

Peripheral Benzodiazepine Receptor ◽

Positron Emission

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Synthesis and biological evaluation of a series of novel N- or O-fluoroalkyl derivatives of tropane: potential positron emission tomography (PET) imaging agents for the dopamine transporter

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(01)00626-6 ◽

2001 ◽

Vol 11 (23) ◽

pp. 3049-3053 ◽

Cited By ~ 22

Author(s):

Xiao-Hui Gu ◽

Rushi Zong ◽

Nora S Kula ◽

Ross J Baldessarini ◽

John L Neumeyer

Keyword(s):

Positron Emission Tomography ◽

Dopamine Transporter ◽

Pet Imaging ◽

Biological Evaluation ◽

Emission Tomography ◽

Imaging Agents ◽

Positron Emission ◽

Synthesis And Biological Evaluation ◽

Derivatives Of

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Stereoselective synthesis and biological evaluation of syn-1-amino-3-[18F]fluorocyclobutyl-1-carboxylic acid as a potential positron emission tomography brain tumor imaging agent

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2009.01.032 ◽

2009 ◽

Vol 17 (5) ◽

pp. 1982-1990 ◽

Cited By ~ 23

Author(s):

Weiping Yu ◽

Larry Williams ◽

Vernon M. Camp ◽

Eugene Malveaux ◽

Jeffrey J. Olson ◽

...

Keyword(s):

Positron Emission Tomography ◽

Brain Tumor ◽

Carboxylic Acid ◽

Stereoselective Synthesis ◽

Tumor Imaging ◽

Biological Evaluation ◽

Emission Tomography ◽

Imaging Agent ◽

Positron Emission ◽

Synthesis And Biological Evaluation

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