CsF in Organic Synthesis. Malonic Ester Synthesis Revisited for Stereoselective Carbon-Carbon Bond Formation

1995 ◽  
Vol 60 (8) ◽  
pp. 2627-2629 ◽  
Author(s):  
Tsuneo Sato ◽  
Junzo Otera
Author(s):  
Jie Jack Li ◽  
Chris Limberakis ◽  
Derek A. Pflum

Searching for reaction in organic synthesis has been made much easier in the current age of computer databases. However, the dilemma now is which procedure one selects among the ocean of choices. Especially for novices in the laboratory, it becomes a daunting task to decide what reaction conditions to experiment with first in order to have the best chance of success. This collection intends to serve as an "older and wiser lab-mate" one could have by compiling many of the most commonly used experimental procedures in organic synthesis. With chapters that cover such topics as functional group manipulations, oxidation, reduction, and carbon-carbon bond formation, Modern Organic Synthesis in the Laboratory will be useful for both graduate students and professors in organic chemistry and medicinal chemists in the pharmaceutical and agrochemical industries.


RSC Advances ◽  
2015 ◽  
Vol 5 (22) ◽  
pp. 16801-16814 ◽  
Author(s):  
Zhi Guan ◽  
Ling-Yu Li ◽  
Yan-Hong He

This article reviews the hydrolase-catalyzed asymmetric carbon–carbon bond-forming reactions for the preparation of enantiomerically enriched compounds in organic synthesis.


2015 ◽  
Vol 137 (51) ◽  
pp. 16163-16171 ◽  
Author(s):  
Taro Hamasaki ◽  
Yuka Aoyama ◽  
Junichi Kawasaki ◽  
Fumitoshi Kakiuchi ◽  
Takuya Kochi

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