Cyclopropane-Derived Peptidomimetics. Design, Synthesis, and Evaluation of Novel Ras Farnesyltransferase Inhibitors

2001 ◽  
Vol 66 (5) ◽  
pp. 1657-1671 ◽  
Author(s):  
Michael C. Hillier ◽  
James P. Davidson ◽  
Stephen F. Martin
Keyword(s):  
Farnesyltransferase Inhibitors ◽  
Design Synthesis ◽  
Ras Farnesyltransferase

Synthese und In-vitro-Evaluierung des Ras-Farnesyltransferase-Inhibitors Pepticinnamin E

1998 ◽  
Vol 110 (9) ◽  
pp. 1298-1301 ◽  
Author(s):  
Klaus Hinterding ◽  
Patrizia Hagenbuch ◽  
Janos Rétey ◽  
Herbert Waldmann
Keyword(s):  
Farnesyltransferase Inhibitors ◽  
Ras Farnesyltransferase

Ras farnesyltransferase inhibitors

1999 ◽  
Vol 24 (10) ◽  
pp. 1099 ◽  
Author(s):  
D.M. Leonard ◽  
J.S. Sebolt-Leopold
Keyword(s):  
Farnesyltransferase Inhibitors ◽  
Ras Farnesyltransferase

Design, synthesis, and activity of achiral analogs of 2-quinolones and indoles as non-thiol farnesyltransferase inhibitors

2005 ◽  
Vol 15 (8) ◽  
pp. 2033-2039 ◽  
Author(s):  
Qun Li ◽  
Keith W. Woods ◽  
Weibo Wang ◽  
Nan-Horng Lin ◽  
Akiyo Claiborne ◽  
...  
Keyword(s):  
Farnesyltransferase Inhibitors ◽  
Design Synthesis

Design, synthesis, and structure–activity relationships of tetrahydroquinoline-based farnesyltransferase inhibitors

2005 ◽  
Vol 15 (7) ◽  
pp. 1895-1899 ◽  
Author(s):  
Louis J. Lombardo ◽  
Amy Camuso ◽  
John Clark ◽  
Krista Fager ◽  
Johnni Gullo-Brown ◽  
...  
Keyword(s):  
Farnesyltransferase Inhibitors ◽  
Design Synthesis ◽  
Structure Activity Relationships ◽  
Structure Activity
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