Acylations with the Acid Chlorides of 2,5-Diphenylfuran-3,4-dicarboxylic Acid and 2,5-Dimethylfuran-3,4-dicarboxylic Acid and Related Compounds

1959 ◽  
Vol 24 (4) ◽  
pp. 497-500 ◽  
Author(s):  
DOROTHY V. NIGHTINGALE ◽  
BERNARD SUKORNICK
Keyword(s):  
Dicarboxylic Acid ◽  
Acid Chlorides ◽  
Related Compounds

Noncataleptic neuroleptic agents: 2-(4-(2-(2-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yloxy)ethyl)piperazine-1-yl)ethanol and some related compounds

1988 ◽  
Vol 53 (11) ◽  
pp. 2731-2741 ◽  
Author(s):  
Jiří Jílek ◽  
Martin Valchář ◽  
Jiří Holubek ◽  
Nataša Dlohožková ◽  
Josef Pomykáček ◽  
...  
Keyword(s):  
Preclinical Studies ◽  
Acid Chlorides ◽  
Substitution Reactions ◽  
Related Compounds

10-(2-Bromoethoxy)-2-chloro-10,11-dihydrodibenzo[b,f]thiepin (X), prepared by two methods, was subjected to substitution reactions with 2-(1-piperazinyl)ethanol, 3-(1-piperazinyl)propanol, 1-methylpiperazine, 3-(1-piperazinyl)propionamide, piperazine, and 1-(ethoxycarbonyl)piperazine and gave the title compounds II-VII. The alcohol II was esterified by treatment with acid chlorides to compounds VIII and IX. Compounds II, V, and VIII proved to be noncataleptic neuroleptic agents and II (clopithepin, VÚFB-17 076) was selected for preclinical studies.

Synthesis of aromatic polyketones by nonstoichiometric Friedel–Crafts polycondensation using AlCl3

2020 ◽  
Vol 11 (26) ◽  
pp. 4221-4227
Author(s):  
Kazuya Matsumoto ◽  
Chisa Fukui ◽  
Riku Shoji ◽  
Mitsutoshi Jikei
Keyword(s):  
Dicarboxylic Acid ◽  
Acid Chlorides ◽  
Aromatic Dicarboxylic Acid

Aromatic polyketones were successfully synthesized by Friedel–Crafts acylation using AlCl3 between aromatic dicarboxylic acid chlorides and 2,2′-dimethoxybiphenyl under both stoichiometric and nonstoichiometric conditions.

ChemInform Abstract: Synthesis of 3,5-Isoxazolidinediones and 1H-2,3-Benzoxazine-1,4(3H)-diones from Aliphatic Oximes and Dicarboxylic Acid Chlorides.

ChemInform ◽  
2014 ◽  
Vol 45 (39) ◽  
pp. no-no
Author(s):  
Robert A. Izydore ◽  
Joseph T. Jones ◽  
Benjamin Mogesa ◽  
Ira N. Swain ◽  
Ronda G. Davis-Ward ◽  
...  
Keyword(s):  
Dicarboxylic Acid ◽  
Acid Chlorides
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