Solution-Phase Synthesis of a HinderedN-Methylated Tetrapeptide Using Bts-Protected Amino Acid Chlorides:  Efficient Coupling and Methylation Steps Allow Purification by Extraction

2000 ◽  
Vol 65 (8) ◽  
pp. 2309-2318 ◽  
Author(s):  
Edwin Vedejs ◽  
Chutima Kongkittingam
Keyword(s):  
Amino Acid ◽  
Solution Phase ◽  
Acid Chlorides ◽  
Phase Synthesis ◽  
Protected Amino Acid ◽  
Solution Phase Synthesis ◽  
Efficient Coupling

Gram-Scale Solution-Phase Synthesis of Heptapeptide Side Chain of Teixobactin

Synlett ◽  
2019 ◽  
Vol 30 (20) ◽  
pp. 2268-2272 ◽  
Author(s):  
Sangeetha Donikela ◽  
Kiranmai Nayani ◽  
Vishnuvardhan Nomula ◽  
Prathama S. Mainkar ◽  
Srivari Chandrasekhar
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Natural Product ◽  
Solution Phase ◽  
Side Chain ◽  
Phase Synthesis ◽  
Solution Phase Synthesis ◽  
Efficient Coupling ◽  
Scalable Synthesis

We report herein a scalable synthesis of linear heptapeptide side chain of the depsipeptide natural product teixobactin through solution phase. The synthesis of heptapeptide was achieved through an efficient coupling of suitably protected tripeptide and tetrapeptide comprising of three d-amino acids and four usual l-amino acid subunits.

Solution phase synthesis of (1→5)-amide linked sugar amino acid dimers derived from sialic acids

1997 ◽  
Vol 38 (9) ◽  
pp. 1493-1496 ◽  
Author(s):  
Jacquelyn Gervay ◽  
Terrence M. Flaherty ◽  
Can Nguyen
Keyword(s):  
Amino Acid ◽  
Sialic Acids ◽  
Solution Phase ◽  
Phase Synthesis ◽  
Solution Phase Synthesis

Solid Phase and Solution Phase Synthesis of Gamma Amino Acid Homo-Oligomers and Mixed Oligomers

2011 ◽  
Vol 17 (2) ◽  
pp. 113-121 ◽  
Author(s):  
K. M. Bhaskara Reddy ◽  
Dokka Mallikarjunasarma ◽  
Kamana Bulliraju ◽  
Vanjivaka Sreelatha ◽  
Y. Bharathi Kumari ◽  
...  
Keyword(s):  
Amino Acid ◽  
Solid Phase ◽  
Solution Phase ◽  
Phase Synthesis ◽  
Solution Phase Synthesis
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