Formal Synthesis of Merrilactone A Using a Domino Cyanide 1,4-Addition–Aldol Cyclization

2012 ◽  
Vol 14 (14) ◽  
pp. 3720-3723 ◽  
Author(s):  
Naim Nazef ◽  
Robert D. M. Davies ◽  
Michael F. Greaney

Synthesis ◽  
2018 ◽  
Vol 50 (22) ◽  
pp. 4359-4368 ◽  
Author(s):  
Brian Stoltz ◽  
Christian Defieber ◽  
Justin Mohr ◽  
Gennadii Grabovyi

A short enantioselective formal synthesis of the antibiotic natural product platencin is reported. Key steps in the synthesis include enantioselective decarboxylation alkylation, aldehyde/olefin radical cyclization, and regioselective aldol cyclization.



Author(s):  
Benjamin J. Huffman ◽  
Tiffany Chu ◽  
Yusuke Hanaki ◽  
Jonathan Wong ◽  
Shuming Chen ◽  
...  


2021 ◽  
Author(s):  
Benjamin J. Huffman ◽  
Tiffany Chu ◽  
Yusuke Hanaki ◽  
Jonathan Wong ◽  
Shuming Chen ◽  
...  


Tetrahedron ◽  
2008 ◽  
Vol 64 (34) ◽  
pp. 7896-7901 ◽  
Author(s):  
Isabel Villanueva Margalef ◽  
Leszek Rupnicki ◽  
Hon Wai Lam


2019 ◽  
Author(s):  
Johannes Schwan ◽  
Merlin Kleoff ◽  
Philipp Heretsch ◽  
Mathias Christmann

A concise synthesis of yaequinolones J1 and J2 is reported. The route is based on the aryne insertion into the σ- C–N-bond of an unsymmetric imide followed by a diastereoselective aldol cyclization of the resulting N-acylated aminobenzophenone. The chromene motif is generated in the first step by an organocatalytic tandem Knoevenagel-electrocyclization of citral and 2-bromoresorcinol. The approach adheres to the ideality-principle, using almost exclusively strategic bond-forming<br>reactions.



Author(s):  
Prakash T. Parvatkar ◽  
Perunninakulath S. Parameswaran ◽  
Debasish Bandyopadhyay ◽  
Sanghamitra Mukherjee ◽  
Bimal K. Banik


Synfacts ◽  
2020 ◽  
Vol 16 (10) ◽  
pp. 1136
Keyword(s):  




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