The role of the atopy patch test (APT) in diagnosis of food allergy in infants and children with atopic dermatitis

2001 ◽  
Vol 12 ◽  
pp. 37-40 ◽  
Author(s):  
Bodo Niggemann
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Patch Test ◽  
Infants And Children ◽  
Atopy Patch Test ◽  
In Infants And Children

Diagnostic Role of the Atopy Patch Test in Children with Atopic Dermatitis and Food Allergy

2006 ◽  
Vol 117 (2) ◽  
pp. S237
Author(s):  
L.M. Brunetti ◽  
R. Tesse ◽  
M. Lore ◽  
M. Leone ◽  
R. Procacci ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Patch Test ◽  
Atopy Patch Test ◽  
Diagnostic Role

The diagnostic value of Atopy Patch Test and Skin Prick Test in children with atopic dermatitis and suspected food allergy

2006 ◽  
Vol 38 (10) ◽  
pp. A93
Author(s):  
Francavilla Ruggiero ◽  
Lorè Maria ◽  
Leone Maddalena ◽  
Miniello Vito ◽  
Fanelli Margherita ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Skin Prick Test ◽  
Patch Test ◽  
Diagnostic Value ◽  
Atopy Patch Test ◽  
Prick Test

scholarly journals Atopy Patch Test in the Diagnosis of Food Allergy in Children with Atopic Dermatitis

2006 ◽  
Vol 49 (4) ◽  
pp. 199-201 ◽  
Author(s):  
Miloš Jeseňák ◽  
Peter Bánovčin
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Patch Test ◽  
Task Force ◽  
Allergic Diseases ◽  
Food Allergies ◽  
Controlled Clinical Trial ◽  
Atopy Patch Test ◽  
Food Allergens ◽  
Additional Tool

Atopic eczema/dermatitis syndrome (AEDS) is one of the most common chronic allergic diseases in children. Among the allergens found to be relevant in AEDS, aeroallergens and food allergens are the most important. The exposure of these patients to their relevant protein allergens can trigger an exacerbation or maintain the disease. AEDS is frequently associated with food allergy, which complicates the management in approximately 40% of these children. Atopy patch test (APT) can help in detecting food allergies in children with AEDS. The earliest publication on patch testing in eczema was described in 1937 by Rostenberg, but the first controlled clinical trial was provided by Mitchell in 1982. APT with food allergens were introduced into clinical use in 1996 by the group of Isolauri. APT test is performed epicutaneously with typical immediate-type allergens (aeroallergens or foods). As a number of apparently minor test modifications greatly influence the sensitivity, specificity, and reproducibility of the APT, the European Task Force on Atopic Dermatitis (ETFAD) has developed a standardized APT technique. APT has developed into a valuable additional tool in the diagnostic work-up of food allergy in infants and children with atopic dermatitis.

Proposal for a standardized interpretation of the atopy patch test in children with atopic dermatitis and suspected food allergy

2006 ◽  
Vol 17 (3) ◽  
pp. 213-217 ◽  
Author(s):  
Ralf G. Heine ◽  
Andrea Verstege ◽  
Anne Mehl ◽  
Ute Staden ◽  
Claudia Rolinck-Werninghaus ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Patch Test ◽  
Atopy Patch Test

scholarly journals Atopy patch test (APT) in the diagnosis of food allergy in children with atopic dermatitis

2012 ◽  
Vol 87 (5) ◽  
pp. 724-728 ◽  
Author(s):  
Soloni Afra Pires Levy ◽  
Sergio Duarte Dortas Junior ◽  
Andrea Huguenim Silva Pires ◽  
Augusto Tiaqui Abe ◽  
Solange Oliveira Rodrigues Valle ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Skin Prick Test ◽  
Patch Test ◽  
Late Phase ◽  
Specific Ige ◽  
Atopy Patch Test ◽  
Prick Test ◽  
Occlusion Time ◽  
Specificity And Sensitivity

BACKGROUND: Atopic Dermatitis is a chronic inflammatory skin disease. Food allergens are important in the pathogenesis in 1/3 of the cases. Several mechanisms are involved in the pathogenesis of Atopic Dermatitis. Immediate reactions are identified by both measurement of specific IgE and skin prick test. Atopy Patch Test seems to be relevant in the investigation of patients with suspected delayed-type reactions. OBJECTIVES: To evaluate the standardization of this method concerning allergen concentration, occlusion time and interpretation, and determine the specificity and sensitivity of the Atopy Patch Test according to the skin prick test and specific IgE levels in food allergy diagnosis in children with Atopic Dermatitis. METHODS: Seventy-two children, aged 2-12 years were selected and followed at the allergy clinic of the Hospital São Zacharias. Skin prick test, specific IgE and food Atopy Patch Test (cow's milk, egg, soy and wheat) were carried out. Three groups were submitted to the Atopy Patch Test: (1) Atopic Dermatitis with or without Rhinitis and Asthma; (2) Rhinitis and or Asthma without AD; (3) Healthy individuals. RESULTS: In group 1, 40% of the patients presented positive reactions. The longer the exposure time (48h and 72h), the higher the sensitivity. In group 2, the test was more specific than sensitive for all the extracts, with increased sensitivity the longer the time of exposure (72h). In group 3, 8.3% presented positive tests. CONCLUSION: APT evidenced a great diagnostic value in late-phase reactions to food, with high specificity. It showed to be a specific and reliable tool in comparison with the healthy group's results.

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