scholarly journals External limiting membrane and visual outcome in macular hole repair: spectral domain OCT analysis

Eye ◽  
2011 ◽  
Vol 26 (1) ◽  
pp. 61-69 ◽  
Author(s):  
G Landa ◽  
R C Gentile ◽  
P M T Garcia ◽  
T O Muldoon ◽  
R B Rosen
Keyword(s):  
Macular Hole ◽  
Visual Outcome ◽  
Spectral Domain ◽  
External Limiting Membrane ◽  
Spectral Domain Oct

scholarly journals Vitrectomy for diabetic macular edema and the relevance of external limiting membrane

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ivastinovic Domagoj ◽  
Haas Anton ◽  
Weger Martin ◽  
Seidel Gerald ◽  
Mayer-Xanthaki Christoph ◽  
...  
Keyword(s):  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Visual Outcome ◽  
Internal Limiting Membrane ◽  
Age Related Macular Degeneration ◽  
External Limiting Membrane ◽  
Ilm Peeling ◽  
Spectral Domain Oct ◽  
Age Related

Abstract Purpose To evaluate the relevance of external limiting membrane (ELM) on the visual and morphological results in eyes with diabetic macular edema (DME) that underwent pars plana vitrectomy (PPV) with epiretinal membrane (ERM) and internal limiting membrane (ILM) peeling. Methods Medical records of patients with DME who underwent PPV at our unit between January 2017 and December 2019 were reviewed. We assessed preoperative and postoperative best-corrected visual acuity (BCVA), central macular thickness (CMT) using spectral domain OCT (optical coherence tomography). Exclusion criteria were previous PPV; incomplete data; concomitant diseases including retinal vein occlusion, age-related macular degeneration, uveitis; and a follow-up of less than 12 months. The surgeries were performed using 23- or 27-gauge vitrectomy. The ELM was graded depending on its configuration (grade 0 = intact, grade 1 to 3: disruption of varying extent). Results Ninety-nine eyes were enrolled. The postoperative follow up averaged 23.7 months. The preoperative and final BCVA averaged 0.71 ± 0.28 and 0.52 ± 0.3 logMAR, respectively (p = 0.002). The CMT averaged 515.2 ± 209.1 μm preoperatively and 327 ± 66.1 μm postoperatively (p = 0.001). Eyes with intact ELM (n = 8) had a significantly better BCVA compared to those with ELM disruption (0.28 ± 0.14 vs. 0.7 ± 0.25 logMAR, p = 0.01). The final CMT was similar among the groups (intact ELM: 317 ± 54.6 μm; ELM disruption: 334 ± 75.2, p = 0.31). Conclusions PPV with ERM and ILM peeling is an effective treatment of DME. Eyes with intact ELM preoperatively had a significantly better final visual outcome. To maximize the benefit for patients with DME we recommend early PPV as long as ELM is intact.

scholarly journals Spontaneous closure of pediatric traumatic macular hole: case report and spectral-domain OCT follow-up

2012 ◽  
Vol 75 (4) ◽  
pp. 286-288 ◽  
Author(s):  
Juliana de Filippi Sartori ◽  
Francisco Stefanini ◽  
Nilva Simeren Bueno de Moraes
Keyword(s):  
Case Report ◽  
Macular Hole ◽  
Spontaneous Closure ◽  
Spectral Domain ◽  
Spectral Domain Oct

Evolution from macular pseudohole to lamellar macular hole — spectral domain OCT study

2010 ◽  
Vol 249 (2) ◽  
pp. 175-178 ◽  
Author(s):  
Janusz Michalewski ◽  
Zofia Michalewska ◽  
Krzysztof Dzięgielewski ◽  
Jerzy Nawrocki
Keyword(s):  
Macular Hole ◽  
Spectral Domain ◽  
Lamellar Macular Hole ◽  
Spectral Domain Oct ◽  
Macular Pseudohole

scholarly journals External limiting membrane: retinal structural barrier in diabetic macular edema

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Sandeep Saxena ◽  
Levent Akduman ◽  
Carsten H. Meyer
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Barrier Effect ◽  
External Limiting Membrane ◽  
Ellipsoid Zone ◽  
Structural Barrier ◽  
Sd Oct

AbstractAdvances in spectral-domain optical coherence tomography (SD-OCT) technology have enhanced the understanding of external limiting membrane (ELM) and ellipsoid zone (EZ) in diabetic macular edema. An increase in VEGF has been demonstrated to be associated with sequential ELM and EZ disruption on SD-OCT. An intact ELM is a prerequisite for an intact EZ in DME. Anti-VEGF therapy leads to restoration of barrier effect of ELM. The ELM restores first followed by EZ restoration.

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