Abstract
The widespread usage of optical coherence tomography angiography (OCTA) is hindered by technical gaps including limited field of view (FOV), lack of quantitative flow information, and suboptimal motion correction. We introduce spectrally extended line field (SELF) OCTA that provides advanced solutions to these challenges. SELF-OCTA breaks the speed limitation and achieves two-fold gain in FOV without sacrificing microvascular details and signal strength through parallel imaging. It also relieves the requirement for shorter exposure time in wide-field applications, so that sufficient sensitivity to slow flow is maintained, particularly in spectral-domain OCT. Towards quantitative angiography, the ‘frequency flow’ mechanism overcomes the speed bottleneck by obviating the requirement for superfluous B-scans. In addition, this mechanism facilitates OCTA-data based motion tracking. Since it can be implemented in existing OCT devices without significant hardware modification or affecting existing functions, SELF-OCTA will make non-invasive, wide-field, quantitative, and low-cost angiographic imaging available to larger patient populations.