Donor cell leukemia arising from preleukemic clones with a novel germline DDX41 mutation after allogenic hematopoietic stem cell transplantation

Leukemia ◽  
2017 ◽  
Vol 31 (4) ◽  
pp. 1020-1022 ◽  
Author(s):  
S Kobayashi ◽  
A Kobayashi ◽  
Y Osawa ◽  
S Nagao ◽  
K Takano ◽  
...  
2015 ◽  
Vol 8 (1) ◽  
pp. 5 ◽  
Author(s):  
Lucina Bobadilla-Morales ◽  
Helia J Pimentel-Gutiérrez ◽  
Sergio Gallegos-Castorena ◽  
Jenny A Paniagua-Padilla ◽  
Citlalli Ortega-de-la-Torre ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Erika Maestas ◽  
Shikha Jain ◽  
Patrick Stiff

Chronic myeloid leukemia is a myeloproliferative disorder that may be treated with hematopoietic stem cell transplantation (HSCT). While posttransplantation relapse of disease resulting from a failure to eradicate the patient’s original leukemia could occur, patients may also rarely develop a secondary malignancy or myelodysplastic syndrome (MDS) of donor origin termed donor cell leukemia (DCL). Cases of donor-derived acute myeloid leukemia (AML) or MDS after HSCT or solid tumor transplantation have been published. However, very few cases of donor-derived multiple myeloma (MM) exist. We describe a patient who developed a donor-derived MM following allogeneic HSCT from a sibling donor.


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