Chemical genetic discovery of targets and anti-targets for cancer polypharmacology

Nature ◽

10.1038/nature11127 ◽

2012 ◽

Vol 486 (7401) ◽

pp. 80-84 ◽

Author(s):

Arvin C. Dar ◽

Tirtha K. Das ◽

Kevan M. Shokat ◽

Ross L. Cagan

Keyword(s):

Chemical Genetic ◽

Genetic Discovery

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Faculty Opinions recommendation of Chemical genetic discovery of targets and anti-targets for cancer polypharmacology.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717247975.793153305 ◽

2012 ◽

Author(s):

Hyung Don Ryoo

Keyword(s):

Chemical Genetic ◽

Genetic Discovery

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Faculty Opinions recommendation of Chemical genetic discovery of targets and anti-targets for cancer polypharmacology.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717247975.792702805 ◽

2012 ◽

Author(s):

Gilbert Cote

Keyword(s):

Chemical Genetic ◽

Genetic Discovery

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Faculty Opinions recommendation of Chemical genetic discovery of targets and anti-targets for cancer polypharmacology.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717247975.793455516 ◽

2012 ◽

Author(s):

Youngseok Lee

Keyword(s):

Chemical Genetic ◽

Genetic Discovery

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Faculty Opinions recommendation of Chemical genetic discovery of targets and anti-targets for cancer polypharmacology.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717247975.793453740 ◽

2012 ◽

Author(s):

Giancarlo Vecchio ◽

Rosa Marina Melillo

Keyword(s):

Chemical Genetic ◽

Genetic Discovery

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Faculty Opinions recommendation of Chemical genetic discovery of targets and anti-targets for cancer polypharmacology.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717247975.792502919 ◽

2012 ◽

Author(s):

Sharad Kumar ◽

Donna Denton

Keyword(s):

Chemical Genetic ◽

Genetic Discovery

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Faculty Opinions recommendation of Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1001725.201877 ◽

2004 ◽

Author(s):

Benoit Coulombe

Keyword(s):

Bioactive Compounds ◽

Genetic Interaction ◽

Interaction Data ◽

Chemical Genetic ◽

Cellular Target ◽

Genetic Interaction Data

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Faculty Opinions recommendation of Chemical genetic control of protein levels: selective in vivo targeted degradation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1018357.209534 ◽

2004 ◽

Author(s):

Dennis Hall

Keyword(s):

Genetic Control ◽

Chemical Genetic ◽

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Faculty Opinions recommendation of Chemical-genetic inhibition of a sensitized mutant myosin Vb demonstrates a role in peripheral-pericentriolar membrane traffic.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017525.216463 ◽

2004 ◽

Author(s):

John Kendrick-Jones

Keyword(s):

Membrane Traffic ◽

Chemical Genetic ◽

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Faculty Opinions recommendation of Chemical-genetic inhibition of a sensitized mutant myosin Vb demonstrates a role in peripheral-pericentriolar membrane traffic.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017525.203280 ◽

2004 ◽

Author(s):

Carol Otey

Keyword(s):

Membrane Traffic ◽

Chemical Genetic ◽

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Faculty Opinions recommendation of Chemical genetic identification of the histamine H1 receptor as a stimulator of insulin-induced adipogenesis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1020315.231529 ◽

2004 ◽

Author(s):

Kevin J Luebke

Keyword(s):

Genetic Identification ◽

H1 Receptor ◽

Histamine H1 Receptor ◽

Chemical Genetic

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