Evaluation of Exposure Change of Nonrenally Eliminated Drugs in Patients With Chronic Kidney Disease Using Physiologically Based Pharmacokinetic Modeling and Simulation

Physiologically Based ◽

Use of Physiologically Based Pharmacokinetic Modeling to Evaluate the Effect of Chronic Kidney Disease on the Disposition of Hepatic CYP2C8 and OATP1B Drug Substrates

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.1205 ◽

2018 ◽

Vol 105 (3) ◽

pp. 719-729 ◽

Cited By ~ 18

Author(s):

Ming-Liang Tan ◽

Ping Zhao ◽

Lei Zhang ◽

Yunn-Fang Ho ◽

Manthena V.S. Varma ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Physiologically Based

Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

ACS Nano ◽

10.1021/acsnano.9b08142 ◽

2020 ◽

Vol 14 (3) ◽

pp. 3075-3095 ◽

Cited By ~ 16

Author(s):

Yi-Hsien Cheng ◽

Chunla He ◽

Jim E. Riviere ◽

Nancy A. Monteiro-Riviere ◽

Zhoumeng Lin

Keyword(s):

Modeling And Simulation ◽

Meta Analysis ◽

Simulation Approach ◽

Nanoparticle Delivery ◽

Physiologically Based ◽

Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development

CPT Pharmacometrics & Systems Pharmacology ◽

10.1038/psp.2014.45 ◽

2014 ◽

Vol 3 (11) ◽

pp. 1-13 ◽

Cited By ~ 77

Author(s):

A R Maharaj ◽

A N Edginton

Keyword(s):

Drug Development ◽

Modeling And Simulation ◽

Pediatric Drug ◽

Pediatric Drug Development ◽

Physiologically Based ◽

Best Practice in the Use of Physiologically Based Pharmacokinetic Modeling and Simulation to Address Clinical Pharmacology Regulatory Questions

Clinical Pharmacology & Therapeutics ◽

10.1038/clpt.2012.68 ◽

2012 ◽

Vol 92 (1) ◽

pp. 17-20 ◽

Cited By ~ 127

Author(s):

P Zhao ◽

M Rowland ◽

S-M Huang

Keyword(s):

Clinical Pharmacology ◽

Modeling And Simulation ◽

Best Practice ◽

Physiologically Based ◽

Assessing drug interaction risk of the grapefruit juice component and dietary supplement 6′,7′‐dihydroxybergamottin via physiologically‐based pharmacokinetic modeling and simulation

The FASEB Journal ◽

10.1096/fasebj.27.1_supplement.1103.4 ◽

2013 ◽

Vol 27 (S1) ◽

Author(s):

Garrett Robert Ainslie ◽

Brandon T Gufford ◽

Christina S Won ◽

Kristina K Wolf ◽

Mary F Paine

Keyword(s):

Drug Interaction ◽

Modeling And Simulation ◽

Dietary Supplement ◽

Grapefruit Juice ◽

Physiologically Based ◽

Physiologically-Based Pharmacokinetic Modeling and Simulation to Assess Potential Cytochrome P450 3A4 and Transporter-Mediated Drug−drug Interactions with Prucalopride as Victim

10.26226/morressier.57d6b2b9d462b8028d88ea6f ◽

2016 ◽

Author(s):

Aiqun Li

Keyword(s):

Cytochrome P450 ◽

Drug Interactions ◽

Modeling And Simulation ◽

Cytochrome P450 3A4 ◽

Physiologically Based ◽

Physiologically Based Pharmacokinetic Modeling and Simulation of Sunitinib in Pediatrics

The AAPS Journal ◽

10.1208/s12248-020-0423-x ◽

2020 ◽

Vol 22 (2) ◽

Author(s):

Yanke Yu ◽

Steven G. DuBois ◽

Cynthia Wetmore ◽

Reza Khosravan

Keyword(s):

Modeling And Simulation ◽

Physiologically Based ◽

Predicting Nonlinear Pharmacokinetics of Omeprazole Enantiomers and Racemic Drug Using Physiologically Based Pharmacokinetic Modeling and Simulation: Application to Predict Drug/Genetic Interactions

Pharmaceutical Research ◽

10.1007/s11095-013-1293-z ◽

2014 ◽

Vol 31 (8) ◽

pp. 1919-1929 ◽

Cited By ~ 15

Author(s):

Fang Wu ◽

Lu Gaohua ◽

Ping Zhao ◽

Masoud Jamei ◽

Shiew-Mei Huang ◽

...

Keyword(s):

Modeling And Simulation ◽

Genetic Interactions ◽

Nonlinear Pharmacokinetics ◽

Physiologically Based ◽

Investigating the Impact of Drug Crystallinity in Amorphous Tacrolimus Capsules on Pharmacokinetics and Bioequivalence Using Discriminatory In Vitro Dissolution Testing and Physiologically Based Pharmacokinetic Modeling and Simulation

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2017.12.024 ◽

2018 ◽

Vol 107 (5) ◽

pp. 1330-1341 ◽

Cited By ~ 22

Author(s):

Hitesh S. Purohit ◽

Niraj S. Trasi ◽

Dajun D. Sun ◽

Edwin C.Y. Chow ◽

Hong Wen ◽

...

Keyword(s):

Modeling And Simulation ◽

In Vitro Dissolution ◽

Dissolution Testing ◽

Physiologically Based ◽

The Impact ◽

Dose Adjustment of Quetiapine and Aripiprazole for Pregnant Women Using Physiologically Based Pharmacokinetic Modeling and Simulation

Clinical Pharmacokinetics ◽

10.1007/s40262-020-00962-3 ◽

2020 ◽

Author(s):

Liang Zheng ◽

Shiwei Tang ◽

Rui Tang ◽

Miao Xu ◽

Xuehua Jiang ◽

...

Keyword(s):

Modeling And Simulation ◽

Pregnant Women ◽

Dose Adjustment ◽

Physiologically Based ◽