Modulation of DNA double-strand break repair as a strategy to improve precise genome editing

Oncogene ◽

10.1038/s41388-020-01445-2 ◽

2020 ◽

Vol 39 (41) ◽

pp. 6393-6405 ◽

Author(s):

Ujjayinee Ray ◽

Sathees C. Raghavan

Keyword(s):

Genome Editing ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Target binding and residence: a new determinant of DNA double-strand break repair pathway choice in CRISPR/Cas9 genome editing

Journal of Zhejiang University SCIENCE B ◽

10.1631/jzus.b2000282 ◽

2021 ◽

Vol 22 (1) ◽

pp. 73-86

Author(s):

Yili Feng ◽

Sicheng Liu ◽

Ruodan Chen ◽

Anyong Xie

Keyword(s):

Genome Editing ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Repair Pathway ◽

Dna Double Strand Break ◽

Pathway Choice ◽

Break Repair ◽

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Inhibitors of DNA double-strand break repair at the crossroads of cancer therapy and genome editing

Biochemical Pharmacology ◽

10.1016/j.bcp.2020.114195 ◽

2020 ◽

Vol 182 ◽

pp. 114195

Author(s):

Ujjayinee Ray ◽

Sathees C. Raghavan

Keyword(s):

Cancer Therapy ◽

Genome Editing ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017512.204275 ◽

2004 ◽

Author(s):

Michael B Yaffe

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.10202956.12871066 ◽

2011 ◽

Author(s):

Claire Wyman

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.10202956.11019054 ◽

2011 ◽

Author(s):

Hao Wu ◽

Jixi Li

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1089242.542442 ◽

2007 ◽

Author(s):

Stephen Jackson

Keyword(s):

Chromatin Structure ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

Structure Modulation ◽

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Faculty Opinions recommendation of Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1104438.560671 ◽

2008 ◽

Author(s):

Carlos Telleria

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Nonhomologous End Joining ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of A role for small RNAs in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14263986.790202827 ◽

2012 ◽

Author(s):

Traci Hall

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of A role for small RNAs in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14263986.15779121 ◽

2012 ◽

Author(s):

Luc DesGroseillers

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717988297.793472681 ◽

2013 ◽

Author(s):

Yamini Dalal

Keyword(s):

Chromatin Remodeling ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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